CAJ | 학술논문

目的：了解该地区献血人群红细胞血型意外抗体的发生频率和分布特点，为提高用血安全提供理论依据。方法对2012年1～12月健康献血者进行意外抗体筛查，抗体筛查阳性者做进一步特异性鉴定，并分析其发生频率和分布特点。结果在195404例血液标本中，共检出意外抗体59例，阳性率为0．030％。其中 IgM 抗体52例，阳性率为0．027％；IgG 抗体7例，阳性率为0．004％，男女性别间阳性率比较，女性高于男性，差异均有统计学意义（P＜0．05）。共检出特异性抗体36例，占61．02％，非特异性抗体23例，占38．98％。结论献血人群有一定意外抗体检出率，意外抗体筛查应列入献血者常规检测项目，以保证用血安全。
목적：료해해지구헌혈인군홍세포혈형의외항체적발생빈솔화분포특점，위제고용혈안전제공이론의거。방법대2012년1～12월건강헌혈자진행의외항체사사，항체사사양성자주진일보특이성감정，병분석기발생빈솔화분포특점。결과재195404례혈액표본중，공검출의외항체59례，양성솔위0．030％。기중 IgM 항체52례，양성솔위0．027％；IgG 항체7례，양성솔위0．004％，남녀성별간양성솔비교，녀성고우남성，차이균유통계학의의（P＜0．05）。공검출특이성항체36례，점61．02％，비특이성항체23례，점38．98％。결론헌혈인군유일정의외항체검출솔，의외항체사사응렬입헌혈자상규검측항목，이보증용혈안전。
Objective To understand the occurrence frequency and distribution charactristics of unexpected an-tibody of RBC blood group among blood donors in this area to provide the theoretical basis for improving blood trans -fusion safety .Methods Unexpected antibody screening of RBC blood group was conducted in healthy blood donors in our center from January to December 2012 .The positive donors with antibody screening were performed the further specificity identification and their occurrence frequency and distribution characteristics were analyzed .Results A-mong 195 404 blood samples ,59 cases of unexpected antibodies were screened out with the positive rate of 0 .030% . 52 cases were IgM antibody with the positive rate of 0 .027% ;7 cases were IgG antibody with the positive rate of 0 .004% .The positive rate of women was higher than that of men ,the difference had statistical significance .36 cases of specific antibody were detected ,accounting for 61 .02% ,23 cases were nonspecific antibody ,accounting for 38 .98% .Conclusion Certain detection rate of unexpected antibodies exists among blood donors .Unexpected anti-body screening should be included in the routine test items for ensuring the safety of blood transfusion .