浙江化工
浙江化工
절강화공
ZHEJIANG CHEMICAL INDUSTRY
2014年
1期
7-10
,共4页
4-三氟甲基水杨酸%间三氟甲基苯酚%合成
4-三氟甲基水楊痠%間三氟甲基苯酚%閤成
4-삼불갑기수양산%간삼불갑기분분%합성
4-(trifluoromethyl)salicylic acid%m-trifluoromethylphenol%synthesis
4-三氟甲基水杨酸、间三氟甲基苯酚是农药、医药等的关键原料和中间体。文章综述了4-三氟甲基水杨酸的合成方法；重点介绍了其合成原料-间三氟甲基苯酚的合成方法，包括重氮化水解法、羟基化法、三氟甲基化法、催化氢化法、过氧化氢氧化法等。
4-三氟甲基水楊痠、間三氟甲基苯酚是農藥、醫藥等的關鍵原料和中間體。文章綜述瞭4-三氟甲基水楊痠的閤成方法；重點介紹瞭其閤成原料-間三氟甲基苯酚的閤成方法，包括重氮化水解法、羥基化法、三氟甲基化法、催化氫化法、過氧化氫氧化法等。
4-삼불갑기수양산、간삼불갑기분분시농약、의약등적관건원료화중간체。문장종술료4-삼불갑기수양산적합성방법；중점개소료기합성원료-간삼불갑기분분적합성방법，포괄중담화수해법、간기화법、삼불갑기화법、최화경화법、과양화경양화법등。
4-(Trifluoromethyl)salicylic acid and m-trifluoromethylphenol is critical intermediate and raw material in the field of pesticide, medicine and others. This article summarizes the methods for synthesis of 4-(trifluoromethyl)salicylic acid, also mainly introduces the synthetic methods of m-Trifluoromethylphenol, the synthetic material of 4-(trifluoromethyl)salicylic acid, including the diazotization and hydrolysis of trifluoromethylaniline, the hydroxylation, the trifluoromethylate, the catalytic hydrogenation, the oxidation of bezotrifluoride with hydrogen peroxide, and so on.
