CAJ | 학술논문

目的：探讨抗精子抗体（AsAb）在免疫性不孕不育症患者血清中的检测情况。方法：采用酶联免疫吸附（ELISA）法测定246例不孕不育症患者AsAb，男89例，女157例，其中89对为夫妇，早期自然流产者39例,同时与57例健康正常生育年龄人员作为对照组。其中男31例，女26例。结果：不孕不育患者AsAb阳性率22.36%，明显高于正常对照组（7.02%），男性患者阳性率16.85%，女性患者阳性率25.48%，均高于正常对照组（7.02%）， P<0.05。早期自然流产AsAb阳性率30.77%,高于正常对照组（7.02%），其中不孕不育组女性AsAb阳性率明显高于男性。结论：血清AsAb检测对不孕不育的诊断和治疗具有重要意义。
목적：탐토항정자항체（AsAb）재면역성불잉불육증환자혈청중적검측정황。방법：채용매련면역흡부（ELISA）법측정246례불잉불육증환자AsAb，남89례，녀157례，기중89대위부부，조기자연유산자39례,동시여57례건강정상생육년령인원작위대조조。기중남31례，녀26례。결과：불잉불육환자AsAb양성솔22.36%，명현고우정상대조조（7.02%），남성환자양성솔16.85%，녀성환자양성솔25.48%，균고우정상대조조（7.02%）， P<0.05。조기자연유산AsAb양성솔30.77%,고우정상대조조（7.02%），기중불잉불육조녀성AsAb양성솔명현고우남성。결론：혈청AsAb검측대불잉불육적진단화치료구유중요의의。
Objective:To investigate the anti sperm antibody (AsAb) detection in patients with immune infertility. Methods:using enzyme linked immunosorbent assay (ELISA) was measured in 246 cases of infertility patients AsAb, male 89 cases, female 157 cases, of which 89 of couples, 39 cases of early spontaneous abortion, and at the same time as and 57 normal child-bearing age personnel control group. Male 31 cases, female 26 cases.Results:the positive rate of AsAb 22.36%infertility patients, was significantly higher than that in normal control group (7.02%), the positive rate of male patients and 16.85% female patients, the positive rate of 25.48%, higher than that in the control group (7.02%), P<0.05. The positive rate of AsAb in early spontaneous abortion 30.77%, higher than that of normal control group (7.02%), of which the positive rate of AsAb in female infertility group was higher than that of male. Conclusions:it is an important significance in diagnosis and treatment of detection of serum AsAb in patients with infertility.