CAJ | 학술논문

目的：研究肾移植患者体内的抗人巨细胞病毒（HCM V ）水平和抗氧化低密度脂蛋白质（ox-LDL ）抗体水平的相关性。方法用抗ox-LDL抗体检测试剂盒和 HCM V抗体检测试剂盒分别检测肾移植患者中抗 HC-MV-免疫球蛋白M（IgM）、抗HCMV-免疫球蛋白G（IgG）、抗ox-LDL抗体水平。根据抗ox-LDL抗体水平将患者分为抗ox-LDL抗体高水平组（n＝15）（抗ox-LDL抗体平均值大于或等于25μg/mL）和低水平组（n＝25）（抗ox-LDL抗体平均值小于25μg/mL），以及对照组。比较3个组的抗ox-LDL抗体、抗 HCMV-IgM、抗 HCMV-IgG水平差异。结果3个组抗ox-LDL抗体水平差异有统计学意义（P＜0．05），抗HCMV-IgM与抗 HCMV-IgG水平与抗ox-LDL抗体水平呈正相关性（P＜0．05）。结论 HCMV感染与抗ox-LDL抗体水平有关。
목적：연구신이식환자체내적항인거세포병독（HCM V ）수평화항양화저밀도지단백질（ox-LDL ）항체수평적상관성。방법용항ox-LDL항체검측시제합화 HCM V항체검측시제합분별검측신이식환자중항 HC-MV-면역구단백M（IgM）、항HCMV-면역구단백G（IgG）、항ox-LDL항체수평。근거항ox-LDL항체수평장환자분위항ox-LDL항체고수평조（n＝15）（항ox-LDL항체평균치대우혹등우25μg/mL）화저수평조（n＝25）（항ox-LDL항체평균치소우25μg/mL），이급대조조。비교3개조적항ox-LDL항체、항 HCMV-IgM、항 HCMV-IgG수평차이。결과3개조항ox-LDL항체수평차이유통계학의의（P＜0．05），항HCMV-IgM여항 HCMV-IgG수평여항ox-LDL항체수평정정상관성（P＜0．05）。결론 HCMV감염여항ox-LDL항체수평유관。
Objective To explore the association between levels of anti -human cytomegalovirus (anti-HC-MV) antibody and oxidized low density lipoprotein (ox-LDL) in patients with kidney transplantation .Methods Lev-els of ox-LDL ,anti-HCMV-IgM and anti-HCMV-IgG were detected in patients with kidney transplantation .All en-rolled subjects were divided into three groups according to levels of ox-LDL ,including high level group (n=15 ,with ox-LDL level more than 25μg/mL) ,low level group (n=25 ,with ox-LDL level less than 25μg/mL) ,and the control group .Levels of ox-LDL ,anti-HCMV-IgM ,anti-HCMV-IgG were compared between the three groups .Results The results indicated that levels of ox-LDL were significantly different between the three groups (P<0 .05) .Level of ox-LDL was positively correlated with anti-HCMV-IgM and anti-HCMV-IgG (P<0 .05) .Conclusion There might be association between HCMV infection and level of ox-LDL .