CAJ | 학술논문

为研究杜仲多糖（EOP）对家禽免疫应答的影响，将120只1日龄三黄鸡随机分成A、B、C、D 4组，分别接种含有0、2、5、8 mg/mL EOP的新城疫和禽流感疫苗，检测相关免疫指标的变化。结果显示，添加8 mg/mL EOP能显著提高三黄鸡新城疫和禽流感抗体水平、T淋巴细胞含量和白细胞吞噬指数（P＜0.05），但对三黄鸡免疫器官指数、血清 IgG 含量影响不大（P＞0.05）。可见， EOP对疫苗免疫具有佐剂作用，且EOP的添加量与其佐剂效果有一定的相关性。
위연구두중다당（EOP）대가금면역응답적영향，장120지1일령삼황계수궤분성A、B、C、D 4조，분별접충함유0、2、5、8 mg/mL EOP적신성역화금류감역묘，검측상관면역지표적변화。결과현시，첨가8 mg/mL EOP능현저제고삼황계신성역화금류감항체수평、T림파세포함량화백세포탄서지수（P＜0.05），단대삼황계면역기관지수、혈청 IgG 함량영향불대（P＞0.05）。가견， EOP대역묘면역구유좌제작용，차EOP적첨가량여기좌제효과유일정적상관성。
The present study was aimed to investigate the effects of Eucommia ulmoides Oliv . Polysaccharide(EOP) on immune response of avain .120 1-day-old Sanhuang broilers were ran-domly divided into A ,B ,C and D four groups .The four groups were subsequently inoculated with Newcasttle disease and Avain influenza vaccines supplemented with 0 ,2 ,5 ,8 mg/mL doses of EOP respectively ,and the associated immune parameters were detected .The results indicated that the HI antibody tieters of Newcasttle disease and Avain influenza ,percentage of T lymphocytes and phagocytic index of white blood cells of group D were significantly elevated (P<0 .05)owing to the EOP addition ,whereas the immune organ index and serum IgG content were not affected . It can be inferred that EOP had adjuvant effect on vaccine inoculation and there was some dose-effect relationship between them .