韩山师范学院学报
韓山師範學院學報
한산사범학원학보
JOURNAL OF HANSHAN TEACHERS COLLEGE
2013年
6期
77-86
,共10页
硫化氢%血管舒张%氧化应激%炎症反应
硫化氫%血管舒張%氧化應激%炎癥反應
류화경%혈관서장%양화응격%염증반응
hydrogen sulfide%vasodilatation%oxidative stress%inflammatory response
硫化氢(H2S)已经被公认为一种生理介质,具有各种各样的生物学功能.胱硫醚β-合成酶(Cytathiohineβ-synthase, CBS)、胱硫醚γ-裂解酶(Cytathiohineγ-lyase, CSE)及3-硫基丙酮酸硫基转移酶(3-Mercaptopyruvate Sulfurtransferase,3MST)可利用半胱氨酸或者同型半胱氨酸生成H2S.本文就H2S的产生及其释放机制、血管舒张作用、抗氧化应激及其抗炎症反应等方面做了综述.
硫化氫(H2S)已經被公認為一種生理介質,具有各種各樣的生物學功能.胱硫醚β-閤成酶(Cytathiohineβ-synthase, CBS)、胱硫醚γ-裂解酶(Cytathiohineγ-lyase, CSE)及3-硫基丙酮痠硫基轉移酶(3-Mercaptopyruvate Sulfurtransferase,3MST)可利用半胱氨痠或者同型半胱氨痠生成H2S.本文就H2S的產生及其釋放機製、血管舒張作用、抗氧化應激及其抗炎癥反應等方麵做瞭綜述.
류화경(H2S)이경피공인위일충생리개질,구유각충각양적생물학공능.광류미β-합성매(Cytathiohineβ-synthase, CBS)、광류미γ-렬해매(Cytathiohineγ-lyase, CSE)급3-류기병동산류기전이매(3-Mercaptopyruvate Sulfurtransferase,3MST)가이용반광안산혹자동형반광안산생성H2S.본문취H2S적산생급기석방궤제、혈관서장작용、항양화응격급기항염증반응등방면주료종술.
Hydrogen sulfide (H2S) has been recognized as a physiological mediator with a variety of bi-ological functions. It is produced by three enzymes,cytathiohineβ-synthase (CBS),cytathiohineγ-lyase (CSE) and 3-mercaptopyruvate sulfurtransferase (3MST) along with cysteine aminotransferase.The mech-anism of release and production, vasorelaxant effect, antioxidative stress and anti-inflammatory response of H2S were reviewed in the article.