CAJ | 학술논문

中药是现代药物的重要组成部分，应用现代分析技术鉴别中药材的真伪、评价质量的优劣，是中药现代化、国际化发展的重要内容。本文介绍了1H-NMR代谢组学技术的发展和特点，以及在中药品种鉴定、道地药材评价、炮制加工、适宜采收期等研究中的应用。并在课题组前期研究基础上，对中药质量评价的1H-NMR代谢组学研究的技术方法、关键问题进行了详细的论述，为中药等天然药物的品种鉴定与质量评价提供了方法学参考。
중약시현대약물적중요조성부분，응용현대분석기술감별중약재적진위、평개질량적우렬，시중약현대화、국제화발전적중요내용。본문개소료1H-NMR대사조학기술적발전화특점，이급재중약품충감정、도지약재평개、포제가공、괄의채수기등연구중적응용。병재과제조전기연구기출상，대중약질량평개적1H-NMR대사조학연구적기술방법、관건문제진행료상세적논술，위중약등천연약물적품충감정여질량평개제공료방법학삼고。
Traditional Chinese medicine (TCM) is an important part of modern medicine. Application of modern ana-lytical techniques to identify the authenticity of TCM and evaluate its quality is an important and critical content in the process of the modernization and internationalization of TCM. This paper described the development and charac-teristics of a 1H-NMR-based metabolomics technology, and reviewed its application in the species identification, quality evaluation of "Daodi Y aocai" (i.e., genuine medicinal materials), processing theory and the best harvest time of TCM. Besides, based on previous work, further discussion was given on technical methods and key question of the 1H-NMR metabolomics method. This paper provided a methodological reference for the species identification and quality evaluation of TCM and other herbal medicines.