医学检验与临床
醫學檢驗與臨床
의학검험여림상
MEDICAL LATORATORY SCIENCE AND CLINICES
2014年
1期
23-24,73
,共3页
急性心肌梗死%脂肪酸类%肌钙蛋白
急性心肌梗死%脂肪痠類%肌鈣蛋白
급성심기경사%지방산류%기개단백
Acute myocardial infarction%Fatty acids%Troponin
目的：评价心肌型脂肪酸结合蛋白（H-FABP）试剂盒在急性心肌梗死（AMI）的早期诊断中的价值。方法：采用H-FABP试剂盒对14例胸痛伴心电图ST段抬高患者进行动态检测，同时测定肌钙蛋白I（cTnI），比较H-FABP及cTnI对急性心肌梗死早期诊断的敏感性、时效性。结果：14例患者出院时均确诊为急性心肌梗死，发病1.5~3h、3~6h内H-FABP试剂盒敏感性均为100%，cTnI分别为0%、50%。6~12h及>12h H-FABP试剂盒敏感性为91.7%和37.5%。cTnI分别为100%和87.5%。结论：与cTnI相比，H-FABP试剂盒对急性心肌梗死早期诊断具有更佳的敏感性及时效性。
目的：評價心肌型脂肪痠結閤蛋白（H-FABP）試劑盒在急性心肌梗死（AMI）的早期診斷中的價值。方法：採用H-FABP試劑盒對14例胸痛伴心電圖ST段抬高患者進行動態檢測，同時測定肌鈣蛋白I（cTnI），比較H-FABP及cTnI對急性心肌梗死早期診斷的敏感性、時效性。結果：14例患者齣院時均確診為急性心肌梗死，髮病1.5~3h、3~6h內H-FABP試劑盒敏感性均為100%，cTnI分彆為0%、50%。6~12h及>12h H-FABP試劑盒敏感性為91.7%和37.5%。cTnI分彆為100%和87.5%。結論：與cTnI相比，H-FABP試劑盒對急性心肌梗死早期診斷具有更佳的敏感性及時效性。
목적：평개심기형지방산결합단백（H-FABP）시제합재급성심기경사（AMI）적조기진단중적개치。방법：채용H-FABP시제합대14례흉통반심전도ST단태고환자진행동태검측，동시측정기개단백I（cTnI），비교H-FABP급cTnI대급성심기경사조기진단적민감성、시효성。결과：14례환자출원시균학진위급성심기경사，발병1.5~3h、3~6h내H-FABP시제합민감성균위100%，cTnI분별위0%、50%。6~12h급>12h H-FABP시제합민감성위91.7%화37.5%。cTnI분별위100%화87.5%。결론：여cTnI상비，H-FABP시제합대급성심기경사조기진단구유경가적민감성급시효성。
Objective:To evaluate the diagnostic value of kit of heart-type fatty acid-binding protein (H-FABP) for early detection of acute myocardial infarction(AMI). Methods:H-FABP of serum was tested by H-FABP kit and cardiac troponin I(cTnI) of serum was measured by regular method for 14 patients with chest complaint and ST-segment elevation. The dynamic change of these myocardial indicators for AMI patients, and their diagnostic sensitivity and chronergy in the earlier period of AMI onset were analyzed.Results:The discharge diagnosis of all patients were AMI. The sensitivity of H-FABP kit and cTnI kit at 1.5~3.0h and 3.0~6.0h after AMI onset were 100%,100% and 0%,50%, respectively. At 6.0~12.0h and >12h the sensitivity of H-FABP kit were 91.7%and 37.5%,100%and 87.5%for cTnI, respectively. Conclusions:H-FABP kit is more sensitive in the early diagnosis of AMI within 3 hours and at 6 hours after symptom onset.
