中国保健营养(上旬刊)
中國保健營養(上旬刊)
중국보건영양(상순간)
China Health Care & Nutrition
2013年
11期
6600-6601
,共2页
酮替芬%依美斯汀%季节性变应性结膜炎
酮替芬%依美斯汀%季節性變應性結膜炎
동체분%의미사정%계절성변응성결막염
目的:探讨慢0.025%富马酸酮替芬滴眼液治疗季节性变应性结膜炎患者眼痒、结膜充血的临床疗效。方法将诊断为季节性变应性结膜炎的229例(229只眼)患者随机分为试验组114例,给予进口0.025%富马酸酮替芬滴眼液,对照组115例,给予0.05%依美斯汀滴眼液,均为2次,d,每次1滴,疗程14d。在用药前和用药后(7±1)d,(14+1)d对两组患者的眼痒和结膜充血进行观察评分。结果用药后(7±1)d以及(14-1)d,酮替芬组和依美斯汀组眼痒、结膜充血评分均明显下降,与基线期相比差异有统计学意义(P<0.05);眼痒和结膜充血下降幅度组间(酮替芬一依美斯汀)差异无统计学意义(P>0.05)。结论进口0.025%富马酸酮替芬滴眼液治疗季节性变应性结膜炎患者的眼痒、结膜充血疗效不劣于0.05%依美斯汀滴眼液。
目的:探討慢0.025%富馬痠酮替芬滴眼液治療季節性變應性結膜炎患者眼癢、結膜充血的臨床療效。方法將診斷為季節性變應性結膜炎的229例(229隻眼)患者隨機分為試驗組114例,給予進口0.025%富馬痠酮替芬滴眼液,對照組115例,給予0.05%依美斯汀滴眼液,均為2次,d,每次1滴,療程14d。在用藥前和用藥後(7±1)d,(14+1)d對兩組患者的眼癢和結膜充血進行觀察評分。結果用藥後(7±1)d以及(14-1)d,酮替芬組和依美斯汀組眼癢、結膜充血評分均明顯下降,與基線期相比差異有統計學意義(P<0.05);眼癢和結膜充血下降幅度組間(酮替芬一依美斯汀)差異無統計學意義(P>0.05)。結論進口0.025%富馬痠酮替芬滴眼液治療季節性變應性結膜炎患者的眼癢、結膜充血療效不劣于0.05%依美斯汀滴眼液。
목적:탐토만0.025%부마산동체분적안액치료계절성변응성결막염환자안양、결막충혈적림상료효。방법장진단위계절성변응성결막염적229례(229지안)환자수궤분위시험조114례,급여진구0.025%부마산동체분적안액,대조조115례,급여0.05%의미사정적안액,균위2차,d,매차1적,료정14d。재용약전화용약후(7±1)d,(14+1)d대량조환자적안양화결막충혈진행관찰평분。결과용약후(7±1)d이급(14-1)d,동체분조화의미사정조안양、결막충혈평분균명현하강,여기선기상비차이유통계학의의(P<0.05);안양화결막충혈하강폭도조간(동체분일의미사정)차이무통계학의의(P>0.05)。결론진구0.025%부마산동체분적안액치료계절성변응성결막염환자적안양、결막충혈료효불렬우0.05%의미사정적안액。
Objective To study the clinical curative effect[0.025% slower ketotifen fumarate eye drops in treatment ofpatients with seasonal allergic conjunctivitis , conjunctivalhyperemia eyes itch.Methods the diagnosis of 229 patients with seasonal allergic conjunctivitis(229 eyes)were randomly divided into experimental group 114 cases,give 0.025% imported ketotifen fumarate eye drops,115 cases in the control group,given 0.05% emedastine eye drops,were 2,D,1 drops each time,duration 14D.In the before and after the treatment(7 ±1)d,(14+1)d of the two groups of patients with ocular itching and conjunctival hyperemia were observedscore.Results after treatment(7 ±1)D and(14-1)d,ketotifen group and emedastine group itchy eyes,conjunctival hyperemia scores were significantly decreased,compared with the baseline period,the difference was statistically significant(P<0.05);eye itch and conjunctival hyperemia drop(a group ketotifen emedastine)there was no significant difference(P>0.05).Conclusion 0.025% imported ketotifen fumarate eye drops in patients with seasonal allergic conjunctivitis liquid in the treatment of eye itch , conjunctival congestion effect of non inferiority in 0.05% emedastine eye drops.