CAJ | 학술논문

目的观察冷沉淀在抢救大量输血后凝血异常中的作用.方法对我院2012年3月至6月出现的10例大量输血之后出现凝血功能异常的重伤患者进行冷沉淀治疗,在冷沉淀治疗之后24小时内对患者的生命体征进行观察,在治疗后3～5天进行血浆Fn和凝血情况测定.结果 10例患者在输注冷沉淀之后,患者的凝血酶原时间、凝血酶时间以及部分凝血酶时间均有了明显的缩短.对患者的生命体征进行检查分析,患者的纤维蛋白原含量有所增加,血浆纤维原结合蛋白的水平也得到了明显的提高,两者之间差异有统计学意义(P＜0.05).结论对患者采取冷沉淀治疗,能够有效改善患者输血后凝血异常的情况,值得在临床上推广应用.
목적 관찰랭침정재창구대량수혈후응혈이상중적작용.방법 대아원2012년3월지6월출현적10례대량수혈지후출현응혈공능이상적중상환자진행랭침정치료,재랭침정치료지후24소시내대환자적생명체정진행관찰,재치료후3～5천진행혈장Fn화응혈정황측정.결과 10례환자재수주랭침정지후,환자적응혈매원시간、응혈매시간이급부분응혈매시간균유료명현적축단.대환자적생명체정진행검사분석,환자적섬유단백원함량유소증가,혈장섬유원결합단백적수평야득도료명현적제고,량자지간차이유통계학의의(P＜0.05).결론 대환자채취랭침정치료,능구유효개선환자수혈후응혈이상적정황,치득재림상상추엄응용.
Objective To observe the effect of cryoprecipitate in rescuing patients after massive blood transfusion in blood coagulation abnormalities.Methods 10 cases of massive blood transfusion appearing abnormal coagulation function of injured patients were given cryoprecipitate treatment in our hospital from March to June 2012.The vital signs of patients were observed after the cryoprecipitate treatment within 24 hours,determination of plasma Fn and blood coagulation condition 3-5 days after treatment.Results Prothrombin time,thrombin time and partial thromboplastin time in 10 patients were obviously shortened after the cryoprecipitate treatment.Inspection and analysis on the vital signs of the patients,the content of fibrinogen in patients increased,plasma fibrinogen binding protein levels can be significantly improved,the different determination was statistically significant (P ＜ 0.05).Conclusion Taking the cryoprecipitate treatment on patients can effectively improve their blood coagulation abnormalities after blood transfusion,which is worthy in the clinical application.