国际生物制品学杂志
國際生物製品學雜誌
국제생물제품학잡지
INTERNATIONAL JOURNAL OF BIOLOGICALS
2014年
2期
93-96
,共4页
受体,表皮生长因子%抗体,单克隆%肿瘤治疗方案
受體,錶皮生長因子%抗體,單剋隆%腫瘤治療方案
수체,표피생장인자%항체,단극륭%종류치료방안
Receptor,epidermal growth factor%Antibodies,monoclonal%Antineoplastic protocols
人表皮生长因子受体3(human epidermal growth factor receptor 3,HER3)是Ⅰ型跨膜酪氨酸激酶受体,在多种肿瘤中表达上调.此文就HER3的结构特征、HER3与肿瘤的关系以及抗HER3抗体的抗肿瘤作用进行简要综述.
人錶皮生長因子受體3(human epidermal growth factor receptor 3,HER3)是Ⅰ型跨膜酪氨痠激酶受體,在多種腫瘤中錶達上調.此文就HER3的結構特徵、HER3與腫瘤的關繫以及抗HER3抗體的抗腫瘤作用進行簡要綜述.
인표피생장인자수체3(human epidermal growth factor receptor 3,HER3)시Ⅰ형과막락안산격매수체,재다충종류중표체상조.차문취HER3적결구특정、HER3여종류적관계이급항HER3항체적항종류작용진행간요종술.
Human epidermal growth factor receptor 3 (HER3) is a type Ⅰ transmembrane tyrosine kinase receptor.HER3 gene expression is up-regulated in a variety of tumors.This article briefly reviews the structural characteristics of HER3,the relationship between HER3 and tumorigenesis,and anti-tumor effect of antibody against HER3.