CAJ | 학술논문

考察材料表面亲/疏水性能和降解性能是评价其能否适用于生物医学领域的重要指标。主要从材料表面静态水接触角和吸水率综合评价 PAPI-PDLLA的表面亲/疏水性,从材料降解过程中失重率测定、分子量测定、p H 值变化和表面形貌观察综合评价 PAPI-PDLLA的降解性能。实验结果表明,通过调节亲水嵌段聚(乙二醇-co-均苯四甲酸酐)亚胺(PAPI)在材料中占的比重,可以调节材料的亲/疏水性能,并且还可缓解PDLLA降解过程中出现的酸性积累问题。因而,PAPI-PDLLA已具备应用于生物医学领域的基础。
고찰재료표면친/소수성능화강해성능시평개기능부괄용우생물의학영역적중요지표。주요종재료표면정태수접촉각화흡수솔종합평개 PAPI-PDLLA적표면친/소수성,종재료강해과정중실중솔측정、분자량측정、p H 치변화화표면형모관찰종합평개 PAPI-PDLLA적강해성능。실험결과표명,통과조절친수감단취(을이순-co-균분사갑산항)아알(PAPI)재재료중점적비중,가이조절재료적친/소수성능,병차환가완해PDLLA강해과정중출현적산성적루문제。인이,PAPI-PDLLA이구비응용우생물의학영역적기출。
Investigation of the surface hydrophilic/hydrophobic properties and degradation properties was to e-valuate material can be applied to biomedical field.PAPI-PDLLA surface hydrophilic/hydrophobic was evalua-ted by the material surface static water contact angle and water absorption comprehensive.PAPI - PDLLA degradation property was characterized by determination of weight-loss ratio,molecular weight,pH,surface morphology.Experimental results show that,the degradation of PDLLA performance by adj usting the hydro-philic block PAPI accounted for the proportion in the material,and adj usting the hydrophilic/hydrophobic prop-erties,and it also can ease the PDLLA appeared in the process of degradation of acid accumulation problem. Therefore,PAPI-PDLLA will be applied in the field of biomedical.