CAJ | 학술논문

目的：了解宜宾地区儿童血脂水平和血脂异常现状，为儿童期预防心血管疾病提供科学依据。方法随机选取宜宾地区健康儿童410例，根据年龄分为4个组，用日立7600-020全自动生化分析仪检测血清三酰甘油（TG）、总胆固醇（TC）、高密度脂蛋白胆固醇（HDL-C）及低密度值蛋白胆固醇（LDL-C）浓度。结果宜宾地区12岁以内儿童TG、TC、HDL-C 与LDL-C 血脂浓度分别为（0．92±0．46）mmol/L、（3．77±0．73）mmol/L、（1．17±0．33）mmol/L、（2．22±0．65）mmol/L，异常率分别为1．46％、3．17％、21．46％、6．34％。儿童总异常率25．12％，3～12岁儿童总异常率20．73％。12岁以内不同性别儿童TG 、TC、HDL-C、LDL-C浓度差异无统计学意义（P＞0．05）。结论 TG、TC、LDL-C异常率虽较其他地区报道略低。但儿童 HDL-C、血脂总异常率远高于其他地区，虽可能由于选取的儿童年龄不一致造成，但儿童血脂紊乱仍有一定的比例。采取综合措施预防儿童血脂紊乱很有必要。
목적：료해의빈지구인동혈지수평화혈지이상현상，위인동기예방심혈관질병제공과학의거。방법수궤선취의빈지구건강인동410례，근거년령분위4개조，용일립7600-020전자동생화분석의검측혈청삼선감유（TG）、총담고순（TC）、고밀도지단백담고순（HDL-C）급저밀도치단백담고순（LDL-C）농도。결과의빈지구12세이내인동TG、TC、HDL-C 여LDL-C 혈지농도분별위（0．92±0．46）mmol/L、（3．77±0．73）mmol/L、（1．17±0．33）mmol/L、（2．22±0．65）mmol/L，이상솔분별위1．46％、3．17％、21．46％、6．34％。인동총이상솔25．12％，3～12세인동총이상솔20．73％。12세이내불동성별인동TG 、TC、HDL-C、LDL-C농도차이무통계학의의（P＞0．05）。결론 TG、TC、LDL-C이상솔수교기타지구보도략저。단인동 HDL-C、혈지총이상솔원고우기타지구，수가능유우선취적인동년령불일치조성，단인동혈지문란잉유일정적비례。채취종합조시예방인동혈지문란흔유필요。
Objective To study serum lipid levels and abnormal rates of serum lipid in children in Yibin area,and to provide the scientific basis for preventing cardiovascular disease.Methods 410 healthy children were enrolled randomly from Yibin area and di-vided into 4 groups based on age.Triglyceride(TG),total serum cholesterol(TC),high density lipoprotein cholesterol(HDL-C)and low density lipoprotein cholesterol(LDL-C)were detected by HITACHI 7600-020 automatic biochemistry analyzer.Results For children within 12 years old in Yibin area,the mean values of TG,TC,HDL-C and LDL-C in serum were (0.92±0.46)mmol/L, (3.77±0.73)mmol/L,(1.17±0.33)mmol/L and (2.22±0.65)mmol/L,respectively.Abnormal rates of serum lipid were 1. 46%,3.17%,21.46% and 6.34%,respectively.Total abnormal rate was 25.12%,and abnormal rate was 20.73% for children aged 3-12 years.There was no significant difference between two genders(P>0.05).Conclusion Abnormal rates of TG,TC, LDL-C are lower than other regions in China.Abnormal rate of HDL-C and total abnormal rate are higher than other regions, though it could be caused by the difference in age of chosen children.However there is a certain abnormal rate in children.That is necessary to take comprehensive measures of preventing children blood lipid disorder.