CAJ | 학술논문

目的：探讨大肠埃希菌在尿路感染者中的分布特点及药敏情况。方法随机选择整理2012年1～12月尿路感染患者尿细菌培养中分离出来的革兰阴性杆菌112例，对其进行细菌鉴定和药敏试验，对结果进行综合分析。结果＞40～70岁年龄段的尿路感染患者随着年龄的增长其感染大肠埃希菌的比例呈现上升趋势。分离出的112例大肠埃希菌中，共有45株产生了超广谱β-内酰胺酶（ESBLs），占40．2％。亚胺培南和美罗培南对大肠埃希菌的敏感性为100．0％，其次为阿米卡星（91．1％）、哌拉西林/他唑巴坦（84．8％）。结论临床治疗由大肠埃希菌引起的尿路感染时应该以药敏试验结果为依据合理使用抗菌药物，以防止耐药菌株的产生。
목적：탐토대장애희균재뇨로감염자중적분포특점급약민정황。방법수궤선택정리2012년1～12월뇨로감염환자뇨세균배양중분리출래적혁란음성간균112례，대기진행세균감정화약민시험，대결과진행종합분석。결과＞40～70세년령단적뇨로감염환자수착년령적증장기감염대장애희균적비례정현상승추세。분리출적112례대장애희균중，공유45주산생료초엄보β-내선알매（ESBLs），점40．2％。아알배남화미라배남대대장애희균적민감성위100．0％，기차위아미잡성（91．1％）、고랍서림/타서파탄（84．8％）。결론림상치료유대장애희균인기적뇨로감염시응해이약민시험결과위의거합리사용항균약물，이방지내약균주적산생。
Objective To explore the bacterial flora distribution and drug resistance of Escherichia coli LE.coli in the patients with urinary tract infection.Methods 112 cases of Gram-negative bacteria were collected,which isolated from the urine culture of patients with urinary tract infection from January 2012 to December 2012.The bacterial identification and susceptibility testing were proceeded,and then the results were analyzed comprehensively.Results The infection rates of E.coli increased with the age in the >40-70 years old group.45 cases of the E.coli produced the Cextended spectrum beta-lactamases(ESBLs)(40.2%).The sensitive rates of imipenem and meropenem for the E.coli both were 100.0%,that of amikacin was 91.1%,and that of piperacillin/tazobactam was 84.8%.Conclusion Antibiotics should be rationally used according to the results of susceptibility testing in pa-tients with urinary tract infection,in order to prevent the occurrence of drug resistant strains.