国际检验医学杂志
國際檢驗醫學雜誌
국제검험의학잡지
INTERNATIONAL JOURNAL OF LABORATORY MEDICINE
2014年
2期
176-177
,共2页
曹玲%朱凡%曾崇亮
曹玲%硃凡%曾崇亮
조령%주범%증숭량
肝炎病毒,乙型%疾病传播,垂直%母乳喂养%聚合酶链反应
肝炎病毒,乙型%疾病傳播,垂直%母乳餵養%聚閤酶鏈反應
간염병독,을형%질병전파,수직%모유위양%취합매련반응
hepatitis B virus%disease transmission,vertical%breast feeding%polymerase chain reaction
目的：探讨乙型肝炎病毒携带产妇血清 HBV-DNA水平对乳汁和新生儿 HBV-DNA水平的影响，以此指导孕期处理和喂养方式。方法选择2012年1～12月的乙型肝炎病毒携带产妇120例，检测产妇血清、乳汁和新生儿血清中的 HBV-DNA水平，对结果进行综合分析。结果64例产妇血清 HBV-DNA＜500 copies/mL，其乳汁 HBV-DNA 检出阳性为1例，新生儿血清 HBV-DNA 检出阳性1例；29例产妇血清 HBV-DNA水平为500 copies/mL至1．0×106 copies/mL，其中4例乳汁HBV-DNA检出阳性，新生儿血清 HBV-DNA检测均为阴性；27例产妇血清 HBV-DNA水平大于或等于1．0×106 copies/mL，其中25例乳汁 HBV-DNA阳性，1例新生儿血清 HBV-DNA检测阳性。结论产妇血清 HBV-DNA 水平大于或等于1．0×106 copies/mL时，产妇乳汁中的 HBV-DNA阳性检出率将大幅度增加，应该禁止母乳喂养；产妇血清中 HBV-DNA 水平对于宫内传播无明显影响。
目的：探討乙型肝炎病毒攜帶產婦血清 HBV-DNA水平對乳汁和新生兒 HBV-DNA水平的影響，以此指導孕期處理和餵養方式。方法選擇2012年1～12月的乙型肝炎病毒攜帶產婦120例，檢測產婦血清、乳汁和新生兒血清中的 HBV-DNA水平，對結果進行綜閤分析。結果64例產婦血清 HBV-DNA＜500 copies/mL，其乳汁 HBV-DNA 檢齣暘性為1例，新生兒血清 HBV-DNA 檢齣暘性1例；29例產婦血清 HBV-DNA水平為500 copies/mL至1．0×106 copies/mL，其中4例乳汁HBV-DNA檢齣暘性，新生兒血清 HBV-DNA檢測均為陰性；27例產婦血清 HBV-DNA水平大于或等于1．0×106 copies/mL，其中25例乳汁 HBV-DNA暘性，1例新生兒血清 HBV-DNA檢測暘性。結論產婦血清 HBV-DNA 水平大于或等于1．0×106 copies/mL時，產婦乳汁中的 HBV-DNA暘性檢齣率將大幅度增加，應該禁止母乳餵養；產婦血清中 HBV-DNA 水平對于宮內傳播無明顯影響。
목적：탐토을형간염병독휴대산부혈청 HBV-DNA수평대유즙화신생인 HBV-DNA수평적영향，이차지도잉기처리화위양방식。방법선택2012년1～12월적을형간염병독휴대산부120례，검측산부혈청、유즙화신생인혈청중적 HBV-DNA수평，대결과진행종합분석。결과64례산부혈청 HBV-DNA＜500 copies/mL，기유즙 HBV-DNA 검출양성위1례，신생인혈청 HBV-DNA 검출양성1례；29례산부혈청 HBV-DNA수평위500 copies/mL지1．0×106 copies/mL，기중4례유즙HBV-DNA검출양성，신생인혈청 HBV-DNA검측균위음성；27례산부혈청 HBV-DNA수평대우혹등우1．0×106 copies/mL，기중25례유즙 HBV-DNA양성，1례신생인혈청 HBV-DNA검측양성。결론산부혈청 HBV-DNA 수평대우혹등우1．0×106 copies/mL시，산부유즙중적 HBV-DNA양성검출솔장대폭도증가，응해금지모유위양；산부혈청중 HBV-DNA 수평대우궁내전파무명현영향。
Objective To explore the effect on the newborn of maternal HBV-DNA levels in HBV carriers.So as to guide the treatment during pregnancy and breast feeding.Methods 120 cases of puerperas carried HBV were chosen from January 2012 to December 2012.The HBV-DNA levels in maternal serum,breast milk and neonatus serum were detected.And the results were an-alyzed comprehensively.Results The maternal serum HBV-DNA quantity of 64 cases were lower than 500 copies/mL.There was one case of breast milk HBV-DNA positive and one case of neonatal serum HBV-DNA positive.The maternal serum HBV-DNA quantity of 29 cases ranged from 500 copies/mL to <1.0×106 copies/mL,4 cases showed HBV-DNA positive in breast milk,and no one showed HBV-DNA positive in neonatal serum.The maternal serum HBV-DNA quantity of 27 cases were ≥1.0×106 cop-ies/mL,25 cases showed HBV-DNA positive in breast milk,and one case showed HBV-DNA positive in neonatal serum.ConclusionWhen maternal serum HBV-DNA quantity was 1.0×106 copies/mL,the HBV-DNA positive rate in breast milk increases sharp-ly,and breastfeeding should be prohibited.Maternal serum HBV-DNA concentration has little effect on intrauterine transmission.
