CAJ | 학술논문

目的：观察阿加曲班联合参芎葡萄糖治疗进展性脑梗死的临床疗效。方法：将70例进展性脑梗死患者随机分为治疗组和对照组各35例，治疗组给予阿加曲班和参芎葡萄糖联合常规治疗，对照组给予常规治疗，疗程为14天。观察2组治疗前、后美国国立卫生院卒中量表(NIHSS)评分和日常生活活动能力Barthel指数(Barthel)。结果：总有效率治疗组为91.43%，对照组为80.00%。2组相比差异显著（P＜0.05）。 NIHSS评分和Barthel指数治疗后2组均明显改善（P＜0.05），但治疗组改善更明显（P＜0.05）。结论：早期应用阿加曲班联合参芎葡萄糖能提高临床有效率，改善进展性脑梗死的神经功能缺损和日常生活能力。
목적：관찰아가곡반연합삼궁포도당치료진전성뇌경사적림상료효。방법：장70례진전성뇌경사환자수궤분위치료조화대조조각35례，치료조급여아가곡반화삼궁포도당연합상규치료，대조조급여상규치료，료정위14천。관찰2조치료전、후미국국립위생원졸중량표(NIHSS)평분화일상생활활동능력Barthel지수(Barthel)。결과：총유효솔치료조위91.43%，대조조위80.00%。2조상비차이현저（P＜0.05）。 NIHSS평분화Barthel지수치료후2조균명현개선（P＜0.05），단치료조개선경명현（P＜0.05）。결론：조기응용아가곡반연합삼궁포도당능제고림상유효솔，개선진전성뇌경사적신경공능결손화일상생활능력。
Objective:To investigate clinical effects of argatroban and ShenXiong glucose in treating progres-sive cerebral infarction. Methods:All 70 patients were randomly allocated into the treatment group and the control group, the treatment group accepted routine treatment, argatroban and ShenXiong glucose, and the control group rou-tine treatment, one course of the treatment was 14 days. The scales of NIHSS, daily living ability and Barthel index of both groups were observed before and after treating. Results: Total effective rate of the treatment group was 91.43%, higher than 80.00% of the control group, the difference was significant (P<0.05). NIHSS scales and Barthel indexes were improved significantly after treating (P<0.05), and the improvement of the treatment group was more significant (P<0.05). Conclusion:Argatroban applied in the early time and ShenXiong glucose could im-prove clinical effective rate, improve neurologic impairment and daily living ability.