白血病·淋巴瘤
白血病·淋巴瘤
백혈병·림파류
JOURNAL OF LEUKEMIA & LYMPHOMA
2013年
9期
555-557
,共3页
买买提力·依马木%木合拜尔·阿布都尔%王晓敏%李燕
買買提力·依馬木%木閤拜爾·阿佈都爾%王曉敏%李燕
매매제력·의마목%목합배이·아포도이%왕효민%리연
白血病,淋巴细胞,慢性%维吾尔族%临床特征%实验室检查%治疗
白血病,淋巴細胞,慢性%維吾爾族%臨床特徵%實驗室檢查%治療
백혈병,림파세포,만성%유오이족%림상특정%실험실검사%치료
Leukemia,lymphocytic,chronic%Uyghur%Clinical features%Laboratory tests%Therapy
目的 探讨新疆维吾尔自治区维吾尔族慢性淋巴细胞白血病(CLL)患者临床及实验室检查特征.方法 回顾性分析新疆维吾尔自治区人民医院39例维吾尔族CLL患者病例资料,选择同期收治的30例汉族CLL患者作为对照组.结果 69例CLL患者平均发病年龄(64.7±9.0)岁,其中汉族和维吾尔族患者分别为(65.6±10.4)岁和(63.9±7.9)岁,差异无统计学意义(P=0.448)；按Rai分期,低危(0期)6例,中危(Ⅰ、Ⅱ期)24例,高危(Ⅲ、Ⅳ期)39例.其中,维吾尔族高危组CLL患者比较明显高于汉族患者,差异有统计学意义(P=0.039)首诊时白细胞计数和受累淋巴结区≥3个者在汉族和维吾尔族中比较差异有统计学意义(f=2.488,P=0.015; x2=4.194,P=0.041).中位随访38.0个月(8.0 ～ 124.0个月),死亡10例,维吾尔族和汉族患者各5例,均为高危组患者.维吾尔族CLL患者预期5年生存率和中位生存时间分别为(88.0±2.7)％和100.7个月,均短于汉族CLL患者[(94.0±3.0)％和151.1个月],但差异均无统计学意义(x2=2.198、P=0.138; x2=0.583、P=0.445).结论 维吾尔族CLL患者在临床、实验室检查特征及生存等方面与汉族患者比较存在一定差异.
目的 探討新疆維吾爾自治區維吾爾族慢性淋巴細胞白血病(CLL)患者臨床及實驗室檢查特徵.方法 迴顧性分析新疆維吾爾自治區人民醫院39例維吾爾族CLL患者病例資料,選擇同期收治的30例漢族CLL患者作為對照組.結果 69例CLL患者平均髮病年齡(64.7±9.0)歲,其中漢族和維吾爾族患者分彆為(65.6±10.4)歲和(63.9±7.9)歲,差異無統計學意義(P=0.448)；按Rai分期,低危(0期)6例,中危(Ⅰ、Ⅱ期)24例,高危(Ⅲ、Ⅳ期)39例.其中,維吾爾族高危組CLL患者比較明顯高于漢族患者,差異有統計學意義(P=0.039)首診時白細胞計數和受纍淋巴結區≥3箇者在漢族和維吾爾族中比較差異有統計學意義(f=2.488,P=0.015; x2=4.194,P=0.041).中位隨訪38.0箇月(8.0 ～ 124.0箇月),死亡10例,維吾爾族和漢族患者各5例,均為高危組患者.維吾爾族CLL患者預期5年生存率和中位生存時間分彆為(88.0±2.7)％和100.7箇月,均短于漢族CLL患者[(94.0±3.0)％和151.1箇月],但差異均無統計學意義(x2=2.198、P=0.138; x2=0.583、P=0.445).結論 維吾爾族CLL患者在臨床、實驗室檢查特徵及生存等方麵與漢族患者比較存在一定差異.
목적 탐토신강유오이자치구유오이족만성림파세포백혈병(CLL)환자림상급실험실검사특정.방법 회고성분석신강유오이자치구인민의원39례유오이족CLL환자병례자료,선택동기수치적30례한족CLL환자작위대조조.결과 69례CLL환자평균발병년령(64.7±9.0)세,기중한족화유오이족환자분별위(65.6±10.4)세화(63.9±7.9)세,차이무통계학의의(P=0.448)；안Rai분기,저위(0기)6례,중위(Ⅰ、Ⅱ기)24례,고위(Ⅲ、Ⅳ기)39례.기중,유오이족고위조CLL환자비교명현고우한족환자,차이유통계학의의(P=0.039)수진시백세포계수화수루림파결구≥3개자재한족화유오이족중비교차이유통계학의의(f=2.488,P=0.015; x2=4.194,P=0.041).중위수방38.0개월(8.0 ～ 124.0개월),사망10례,유오이족화한족환자각5례,균위고위조환자.유오이족CLL환자예기5년생존솔화중위생존시간분별위(88.0±2.7)％화100.7개월,균단우한족CLL환자[(94.0±3.0)％화151.1개월],단차이균무통계학의의(x2=2.198、P=0.138; x2=0.583、P=0.445).결론 유오이족CLL환자재림상、실험실검사특정급생존등방면여한족환자비교존재일정차이.
Objective To analyze the clinical and laboratory features of Uyghur patients with chronic lymphocytic leukemia(CLL) in Xinjiang Uyghur Autonomous Region.Methods Retrospective investigation of 39 Uyghur patients with CLL in the People' s Hospital of Xinjiang Uyghur Autonomous Region,and analyzed 30 cases of Han nationality patients with CLL choose over the same period as the contrul group.Results The average age of Uyghur and Han nationality CLL patients were (65.6±10.4) years old and (63.9±7.9) years old while the average age was (64.7±9.0) years old of all cases,and there was no statistical significance (P =0.448).By CLL Rai staging,patients in low-risk (phase 0),medium-risk (phase Ⅰ and Ⅱ) and high-risk (phase Ⅲ and Ⅳ) were 6,24 and 39 cases respectively.Among them,Uyghur patients with advanced stage was more than Han nationality patients (P =0.039).The WBC counts in the initial diagnosis and the number of lymph node regions involved ≥3 were statistically significant (t =2.488,P =0.015,x2 =4.194,P =0.041).With a median follow-up time of 38.0 months (8.0-124.0 months),in which 10 cases died,5 cases was Uyghur and 5 cases was Han nationality,and all of them were the high-risk group of CLL patients.The expected 5-year survival rate and the median survival time were (88.0±2.7) ％ and 100.7 months,respectively and both of them shorter than Han nationality patients with CLL [(94.0±3.0) ％ and 151.1 months],but no statistically significant (x2 =2.198,P =0.138,x2 =0.583,P =0.445).Conclusion There are some differences in two nations in the case of characteristics of clinical laboratory examinations and survivals.
