中外医学研究
中外醫學研究
중외의학연구
CHINESE AND FOREIGN MEDICAL RESEARCH
2014年
3期
59-59,60
,共2页
冠心病%同型半胱氨酸%尿酸
冠心病%同型半胱氨痠%尿痠
관심병%동형반광안산%뇨산
Coronary heart disease%UA%Hcy
目的:探讨冠心病患者血清同型半胱氨酸(Hcy)、尿酸(UA)水平变化及临床意义。方法:对74例冠心病患者(稳定型心绞痛26例,不稳定型心绞痛24例,急性心肌梗死24例)和32例健康对照者血清Hcy、UA水平进行检测,并进行比较分析。结果:各组冠心病患者血清UA、Hcy水平均显著高于正常对照组,差异均具有统计学意义(P<0.05);SAP组、UAP组患者血清UA、Hcy水平均显著低于AMI组,差异均有统计学意义(P<0.05);而SAP组患者血清UA、Hcy水平均显著低于UAP组,差异亦均有统计学意义(P<0.05);冠心病患者血清UA与Hcy呈显著正相关(P<0.05)。结论:检测冠心病患者血清Hcy、UA水平,对其病情监控及发病机制的研究具有重要的临床意义。
目的:探討冠心病患者血清同型半胱氨痠(Hcy)、尿痠(UA)水平變化及臨床意義。方法:對74例冠心病患者(穩定型心絞痛26例,不穩定型心絞痛24例,急性心肌梗死24例)和32例健康對照者血清Hcy、UA水平進行檢測,併進行比較分析。結果:各組冠心病患者血清UA、Hcy水平均顯著高于正常對照組,差異均具有統計學意義(P<0.05);SAP組、UAP組患者血清UA、Hcy水平均顯著低于AMI組,差異均有統計學意義(P<0.05);而SAP組患者血清UA、Hcy水平均顯著低于UAP組,差異亦均有統計學意義(P<0.05);冠心病患者血清UA與Hcy呈顯著正相關(P<0.05)。結論:檢測冠心病患者血清Hcy、UA水平,對其病情鑑控及髮病機製的研究具有重要的臨床意義。
목적:탐토관심병환자혈청동형반광안산(Hcy)、뇨산(UA)수평변화급림상의의。방법:대74례관심병환자(은정형심교통26례,불은정형심교통24례,급성심기경사24례)화32례건강대조자혈청Hcy、UA수평진행검측,병진행비교분석。결과:각조관심병환자혈청UA、Hcy수평균현저고우정상대조조,차이균구유통계학의의(P<0.05);SAP조、UAP조환자혈청UA、Hcy수평균현저저우AMI조,차이균유통계학의의(P<0.05);이SAP조환자혈청UA、Hcy수평균현저저우UAP조,차이역균유통계학의의(P<0.05);관심병환자혈청UA여Hcy정현저정상관(P<0.05)。결론:검측관심병환자혈청Hcy、UA수평,대기병정감공급발병궤제적연구구유중요적림상의의。
Objective:To study the clinical significance of detecting serum levels of homocysteine(Hcy),uric acid (UA) in patients with coronary artery disease(CHD).Method:The serum levels of UA and Hcy in 74 cases of patients with CHD(26 patients with stable angina pectoris,24 patients with unstable angina pectoris,24 patients with acute myocardial infarction)and 32 healthy controls were detected and analyzed.Result:The serum levels of UA and Hcy in the CHD groups were significantly higher than those in the control group(P<0.05),the serum levels of UA and Hcy in the SAP group and the UAP group were significantly lower than those in the AMI group(P<0.05).The serum levels of UA and Hcy in the SAP group were significantly lower than those in the UAP group(P<0.05). Conclusion:The detection of serum levels of Hcy,UA in patients with CHD,have important clinical significance in researching on the condition monitoring and pathogenesis.