中外医学研究
中外醫學研究
중외의학연구
CHINESE AND FOREIGN MEDICAL RESEARCH
2014年
3期
45-46
,共2页
连续性血液净化%脓毒血症%急性肾损伤
連續性血液淨化%膿毒血癥%急性腎損傷
련속성혈액정화%농독혈증%급성신손상
Continuous blood purification%Sepsis%Acute kidney injury
目的：探讨连续性血液净化(CBP)治疗脓毒血症合并急性肾损伤的临床疗效。方法：90例脓毒血症合并急性肾损伤患者随机分为高容量组和标准容量组，各45例，行连续性静脉-静脉血液滤过(CVVH)治疗。结果：高容量组、标准容量组治疗后APACHEⅡ评分均明显降低(P<0.05或0.01)，其中高容量组改善幅度更加明显(P<0.05)。两组60 d生存率分别为55.6%、48.9%，组间比较差异无统计学意义(P>0.05)，但高容量组肾功能恢复时间、ICU停留时间均较标准容量组明显短(P<0.05)。结论：高容量CBP的应用能更好地清除炎症细胞因子，促进肾功能恢复，提高生存率，值得推广应用。
目的：探討連續性血液淨化(CBP)治療膿毒血癥閤併急性腎損傷的臨床療效。方法：90例膿毒血癥閤併急性腎損傷患者隨機分為高容量組和標準容量組，各45例，行連續性靜脈-靜脈血液濾過(CVVH)治療。結果：高容量組、標準容量組治療後APACHEⅡ評分均明顯降低(P<0.05或0.01)，其中高容量組改善幅度更加明顯(P<0.05)。兩組60 d生存率分彆為55.6%、48.9%，組間比較差異無統計學意義(P>0.05)，但高容量組腎功能恢複時間、ICU停留時間均較標準容量組明顯短(P<0.05)。結論：高容量CBP的應用能更好地清除炎癥細胞因子，促進腎功能恢複，提高生存率，值得推廣應用。
목적：탐토련속성혈액정화(CBP)치료농독혈증합병급성신손상적림상료효。방법：90례농독혈증합병급성신손상환자수궤분위고용량조화표준용량조，각45례，행련속성정맥-정맥혈액려과(CVVH)치료。결과：고용량조、표준용량조치료후APACHEⅡ평분균명현강저(P<0.05혹0.01)，기중고용량조개선폭도경가명현(P<0.05)。량조60 d생존솔분별위55.6%、48.9%，조간비교차이무통계학의의(P>0.05)，단고용량조신공능회복시간、ICU정류시간균교표준용량조명현단(P<0.05)。결론：고용량CBP적응용능경호지청제염증세포인자，촉진신공능회복，제고생존솔，치득추엄응용。
Objective:To investigate the effects of continuous blood purification (CBP) in the treatment of sepsis and clinical curative effect of acute kidney injury.Method:90 cases of sepsis with acute kidney injury were randomly divided into groups of high capacity group and standard volume group,with 45 cases in each group,continuous veno venous hemofiltration(CVVH) therapy.Result:After treatment,APACHEⅡscore were significantly decreased in two groups(P<0.05 or 0.01),the high capacity group improved more significantly(P<0.05).60 d survival rate of two groups were 55.6%,48.9%,there was no significant difference(P>0.05),but the renal function recovery time,ICU residence time were shorter in high capacity group than the standard volume group(P<0.05). Conclusion:The application of high capacity CBP can better remove inflammatory cytokines,promoting the recovery of renal function in patients,improve the survival rate,it is worthy of popularization and application.
