CAJ | 학술논문

目的：观察二甲双胍联合能量摄入限制治疗非酒精性脂肪肝的疗效。方法：将78例非酒精性脂肪肝患者分为两组，分别给予二甲双胍和多烯磷脂酰胆碱胶囊（易善复）治疗，观察两组每月治疗效果及疗程结束后所有生化指标及肝脏B超。结果：两组患者在临床症状改善、肝功能好转上、总有效率无显著差异（P＞0．05），血脂下降和肝B超改善率有差异性（P＜0．05），不良反应发生率均较低。结论：二甲双胍联合能量摄入控制治疗非酒精性脂肪肝患者疗效、安全性好，且在降血脂方面有一定效果。
목적：관찰이갑쌍고연합능량섭입한제치료비주정성지방간적료효。방법：장78례비주정성지방간환자분위량조，분별급여이갑쌍고화다희린지선담감효낭（역선복）치료，관찰량조매월치료효과급료정결속후소유생화지표급간장B초。결과：량조환자재림상증상개선、간공능호전상、총유효솔무현저차이（P＞0．05），혈지하강화간B초개선솔유차이성（P＜0．05），불량반응발생솔균교저。결론：이갑쌍고연합능량섭입공제치료비주정성지방간환자료효、안전성호，차재강혈지방면유일정효과。
Objective :To observe the metformin combined with energy intake restriction and treatment of non-alcoholic fatty liver .Methods :78 patients with non-alcoholic fatty liver patients were divided into two groups ,were given met-formin and polyene phosphatidyl choline capsules (Essentiale) treatment ,observed two sets of monthly treatment effect after the end of treatment biochemical markers and liver B .Results:The patients in the improvement of clinical symptoms ,liver function improved ,the total effective rate was no significant difference (P>0 .05) ,lipids decreased and liver B-improvement rate differences (P<0 .05) ,adverse reaction rates than is low .Conclusion:Metformin joint energy intake control efficacy in patients with treatment of nonalcoholic fatty liver ,security ,and have some effect in lowering blood pressure .