CAJ | 학술논문

目的：了解神经外科下呼吸道感染病原菌分布特征及耐药性。方法对2075例神经外科下呼吸道感染患者痰标本进行病原菌培养、鉴定和药敏试验检测，分析合并感染病原菌分布特征及耐药性。结果共检出合并感染患者228例，合并感染发病率为10．9％，其中革兰阳性球菌（G＋ c）与G＋ c合并感染2例（0．9％）、G＋ c与革兰阴性杆菌（G - b）合并感染87例（38．2％）、G - b与 G - b合并感染133例（58．3％）、细菌合并真菌感染6例（2．6％）。G＋c以金黄色葡萄球菌为主，检出84株（36．8％），其中耐甲氧西林金黄色葡萄球菌（MRSA）检出44株（19．3％）；G-b以铜绿假单胞菌、肺炎克雷伯菌、鲍曼不动杆菌、大肠埃希菌为主。结论神经外科下呼吸道合并感染多为两种病原菌同时感染所致，多数病原菌具有多重耐药性。
목적：료해신경외과하호흡도감염병원균분포특정급내약성。방법대2075례신경외과하호흡도감염환자담표본진행병원균배양、감정화약민시험검측，분석합병감염병원균분포특정급내약성。결과공검출합병감염환자228례，합병감염발병솔위10．9％，기중혁란양성구균（G＋ c）여G＋ c합병감염2례（0．9％）、G＋ c여혁란음성간균（G - b）합병감염87례（38．2％）、G - b여 G - b합병감염133례（58．3％）、세균합병진균감염6례（2．6％）。G＋c이금황색포도구균위주，검출84주（36．8％），기중내갑양서림금황색포도구균（MRSA）검출44주（19．3％）；G-b이동록가단포균、폐염극뢰백균、포만불동간균、대장애희균위주。결론신경외과하호흡도합병감염다위량충병원균동시감염소치，다수병원균구유다중내약성。
Objective To investigate the distribution characteristics and drug resistance of pathogenic bacteri-um in patients with lower respiratory infections (LRI) in neurosurgery department .Methods Pathogenic bacterium , isolated from patients with LRI in neurosurgery department ,were cultured ,identified and detected for drug resist-ance .Results A total of 228 cases with combined infection were identified ,and the incidence of combined LRI was 10 .9% .Among all combined LRI patients ,2 cases (0 .9% ) were Gram positive coccus (G+c) and G+c combined in-fection ,87 cases (38 .2% ) were G+c and Gram negative bacilli (G -b) combined infection ,133 cases (58 .3% ) G-b and G -b combined infection ,and 6 cases (2 .6% ) were bacteria and fungal combined infection .Staphylococcus aureus was the most prominent in isolated G+c strains ,about 84 strains (36 .8% ) ,and methicillin-resistant Staphylococcus aureus accounted for 44 strains .Pseudomonas aeruginosa ,Klebsiella pneumoniae ,Acinetobacter baumannii and Esche-richia coli were the most prominent in isolated G -b strains .Conclusion Most combined LRI in neurosurgery might be caused by tow pathogenic bacteria ,and most pathogenic bacteria could be multidrug-resistant .