中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2014年
4期
116-117
,共2页
荨麻疹%总IgE%吸入物过敏原过筛试验%食物过敏原过筛试验%特异性IgE
蕁痳疹%總IgE%吸入物過敏原過篩試驗%食物過敏原過篩試驗%特異性IgE
담마진%총IgE%흡입물과민원과사시험%식물과민원과사시험%특이성IgE
Urticaria%TigE%Phadiatop%Fx5E%SIgE
目的：对本院荨麻疹患儿过敏原情况进行分析探讨。方法：采用免疫球蛋白E测定试剂盒（化学发光法）检测血清总IgE （TIgE）和Phadia公司全自动体外变应原检测系统ImmunoCAP250荧光酶联免疫法检测血清吸入物过敏原过筛查试验（Phadiatop）、食物过敏原过筛查试验（Fx5E）和特异性IgE（SIgE）。结果：193例荨麻疹患儿中，TIgE阳性率为99.3%。Phadiatop、Fx5E总计阳性率为59.8%；Phadiatop、Fx5E阳性率分别为32.1%和49.7%。SIgE显示吸入物过敏原以屋尘、粉尘螨、屋尘螨为主（47.6%），食物过敏原以牛奶、鸡蛋为主（56.3%，52.6%）。0~3岁年龄段患儿Fx5E阳性率为45.2%，明显高于Phadiatop的阳性率26.2%（P<0.05）；>3岁患儿中两者无明显差异（P>0.05）。结论：荨麻疹患儿多属特应性体质，约60%与第I型变态反应有关；吸入物过敏原主要为屋尘、粉尘螨、屋尘螨，食物过敏原以牛奶、鸡蛋为主；0~3岁患儿食物过敏是其主要因素，而>3岁患儿食物与吸入物过敏几乎均等存在。
目的：對本院蕁痳疹患兒過敏原情況進行分析探討。方法：採用免疫毬蛋白E測定試劑盒（化學髮光法）檢測血清總IgE （TIgE）和Phadia公司全自動體外變應原檢測繫統ImmunoCAP250熒光酶聯免疫法檢測血清吸入物過敏原過篩查試驗（Phadiatop）、食物過敏原過篩查試驗（Fx5E）和特異性IgE（SIgE）。結果：193例蕁痳疹患兒中，TIgE暘性率為99.3%。Phadiatop、Fx5E總計暘性率為59.8%；Phadiatop、Fx5E暘性率分彆為32.1%和49.7%。SIgE顯示吸入物過敏原以屋塵、粉塵螨、屋塵螨為主（47.6%），食物過敏原以牛奶、鷄蛋為主（56.3%，52.6%）。0~3歲年齡段患兒Fx5E暘性率為45.2%，明顯高于Phadiatop的暘性率26.2%（P<0.05）；>3歲患兒中兩者無明顯差異（P>0.05）。結論：蕁痳疹患兒多屬特應性體質，約60%與第I型變態反應有關；吸入物過敏原主要為屋塵、粉塵螨、屋塵螨，食物過敏原以牛奶、鷄蛋為主；0~3歲患兒食物過敏是其主要因素，而>3歲患兒食物與吸入物過敏幾乎均等存在。
목적：대본원담마진환인과민원정황진행분석탐토。방법：채용면역구단백E측정시제합（화학발광법）검측혈청총IgE （TIgE）화Phadia공사전자동체외변응원검측계통ImmunoCAP250형광매련면역법검측혈청흡입물과민원과사사시험（Phadiatop）、식물과민원과사사시험（Fx5E）화특이성IgE（SIgE）。결과：193례담마진환인중，TIgE양성솔위99.3%。Phadiatop、Fx5E총계양성솔위59.8%；Phadiatop、Fx5E양성솔분별위32.1%화49.7%。SIgE현시흡입물과민원이옥진、분진만、옥진만위주（47.6%），식물과민원이우내、계단위주（56.3%，52.6%）。0~3세년령단환인Fx5E양성솔위45.2%，명현고우Phadiatop적양성솔26.2%（P<0.05）；>3세환인중량자무명현차이（P>0.05）。결론：담마진환인다속특응성체질，약60%여제I형변태반응유관；흡입물과민원주요위옥진、분진만、옥진만，식물과민원이우내、계단위주；0~3세환인식물과민시기주요인소，이>3세환인식물여흡입물과민궤호균등존재。
Objective:To investigate and discuss the situation of allergens in children with urticaria in our hospital. Method:Total serum immunoglobulin(TIgE)was detected by IgE ELISA kit(chemiluminescence). Phadiatop,Fx5E and specific IgE(SIgE)were tested by fully automatic in vitro allergen detection system(ImmunoCAP250,Phadia Company)with fluorescent enzyme-linked immunoassay. Result:In 193 patients with urticaria,99.3%was detected with positive TIgE. The positive rates of Phadiatop and Fx5E were 32.1%and 49.7%separately,and the aggregate of the two rates was 59.8%. Inhalant allergens were mainly consisted of house dust and mites(47.6%)while ingested allergens were primarily composed of milk and eggs(56.3%,52.6%). The positive rate of Fx5E was significantly higher than that of Phadiatop among children 0 to 3 years old(45.2%vs 26.2%, P<0.05),but which in patients aged above 3 years old had no significant difference(P>0.05). Conclusion:Atopic constitution is common in children with urticaria,and approximately 60%cases are related to type I hypersensitivity. Inhalant allergens are mainly composed of house dust and mites,and ingested allergens are mainly composed of milk and eggs. Ingested allergens are the most common reason for urticaria in children 0-3 years old while in children above 3-year,ingested and inhalant allergens are equally important.
