中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2014年
4期
102-103
,共2页
奥美拉唑%反流性食管炎%临床疗效
奧美拉唑%反流性食管炎%臨床療效
오미랍서%반류성식관염%림상료효
Omeprazole%Reflux esophagitis%Clinical effect
目的:探讨奥美拉唑治疗反流性食管炎的临床疗效。方法:选取2011年4-11月本院消化科诊治的80例反流性食管炎患者,按照随机数字表法将其分为联合组和单一组各40例,单一组应用一般常规药物治疗,联合组在常规药物基础上联合奥美拉唑联合治疗。比较两组患者通过治疗后症状缓解时间、不良反应发生率及总有效率。结果:联合组患者治疗后症状缓解时间(15.13±4.2)d明显少于单一组的(21.33±3.6)d,且联合组的不良反应发生率12.5%明显低于单一组的35.0%,而治疗总有效率80.0%明显高于单一组的62.5%,比较差异均有统计学意义(P<0.05)。结论:奥美拉唑治疗反流性食管炎疗效显著,恢复时间快,不良反应少,值得临床推广。
目的:探討奧美拉唑治療反流性食管炎的臨床療效。方法:選取2011年4-11月本院消化科診治的80例反流性食管炎患者,按照隨機數字錶法將其分為聯閤組和單一組各40例,單一組應用一般常規藥物治療,聯閤組在常規藥物基礎上聯閤奧美拉唑聯閤治療。比較兩組患者通過治療後癥狀緩解時間、不良反應髮生率及總有效率。結果:聯閤組患者治療後癥狀緩解時間(15.13±4.2)d明顯少于單一組的(21.33±3.6)d,且聯閤組的不良反應髮生率12.5%明顯低于單一組的35.0%,而治療總有效率80.0%明顯高于單一組的62.5%,比較差異均有統計學意義(P<0.05)。結論:奧美拉唑治療反流性食管炎療效顯著,恢複時間快,不良反應少,值得臨床推廣。
목적:탐토오미랍서치료반류성식관염적림상료효。방법:선취2011년4-11월본원소화과진치적80례반류성식관염환자,안조수궤수자표법장기분위연합조화단일조각40례,단일조응용일반상규약물치료,연합조재상규약물기출상연합오미랍서연합치료。비교량조환자통과치료후증상완해시간、불량반응발생솔급총유효솔。결과:연합조환자치료후증상완해시간(15.13±4.2)d명현소우단일조적(21.33±3.6)d,차연합조적불량반응발생솔12.5%명현저우단일조적35.0%,이치료총유효솔80.0%명현고우단일조적62.5%,비교차이균유통계학의의(P<0.05)。결론:오미랍서치료반류성식관염료효현저,회복시간쾌,불량반응소,치득림상추엄。
Objective:To investigate the clinical efficacy of omeprazole in treating reflux esophagitis.Method:80 patients with reflux esophagitis were selected in our hospital from April 2011 to November 2011,they were randomly divided into the single group and the combination group,40 cases in each group.The single group was given conventional drug treatment,the combination group was combined with omeprazole on the basis of the routine drug.The duration of remission after treatment,the incidence of adverse reactions and the total efficiency of the two groups were compared.Result:The duration of remission after treatment in the combination group was(15.13±4.2)d,it was significantly less than(21.33±3.6)d of the single group;the incidence of adverse reaction in the combination group was 12.5%,it was significantly lower than the single group(35.0%),and the total efficiency of the combination group was 80%,it was higher than that the single group(62.5%),the differences were statistically significant(P<0.05).Conclusion:Omeprazole in treating reflux esophagitis curative effect,faster recovery,less adverse reaction,is worth the clinical promotion.