CAJ | 학술논문

目的：了解抗菌类药物导致不良反应的特点和规律。方法随机抽取2012年1月～2013年1月的144例抗菌药物不良反应患者，并进行回顾性分析。结果144例抗菌药物不良反应患者主要涉及青霉素类、喹诺酮类等9大类抗菌药物；青霉素类药物引起的不良反应患者最多，共50例，占34%，其次为喹诺酮类，共46例，占31.9%。抗菌药物不良反应的引起方式主要为静脉点滴；引起皮肤和附件损伤的为54例，占37.5%，引起消化损伤24例，占16.7%。在抗菌类药物中，青霉素类药物导致不良反应居首位，其次是喹诺酮类。结论通过合理使用抗菌药物，可以有效降低因抗菌药物引发的不良反应，缩短患者的治疗时间，提高患者的生活质量。
목적：료해항균류약물도치불량반응적특점화규률。방법수궤추취2012년1월～2013년1월적144례항균약물불량반응환자，병진행회고성분석。결과144례항균약물불량반응환자주요섭급청매소류、규낙동류등9대류항균약물；청매소류약물인기적불량반응환자최다，공50례，점34%，기차위규낙동류，공46례，점31.9%。항균약물불량반응적인기방식주요위정맥점적；인기피부화부건손상적위54례，점37.5%，인기소화손상24례，점16.7%。재항균류약물중，청매소류약물도치불량반응거수위，기차시규낙동류。결론통과합리사용항균약물，가이유효강저인항균약물인발적불량반응，축단환자적치료시간，제고환자적생활질량。
Objective:To investigate the characteristics and rules of adverse reactions caused by antibacterial drugs; Method:Extract 144 cases of adverse drug reactions of antibiotics randomly from January 2012 to January 2013, and were retrospectively analyzed; Results: 144 ases of adverse drug reactions of antibiotics were mainly related to penicil ins, quinolones and other 7 kinds of antibacterial drugs; adverse reaction caused by penicil ins is the most, a total of 50 cases, accounting for 34%, fol owed by quinolones, a total of 46 cases, accounting for 31.9%. Antimicrobial drug adverse reaction iscaused by intravenous drip; the number who is caused skin and accessory injury is 54 cases, accounting for 37.5%, 24 cases of digestive damage, accounted for 16.7%. In the antibacterial drugs, penicil in drug which causes adverse reaction is in the first place, fol owed by quinolones;Conclusion:The rational use of antimicrobial drugs can effectively reduce the adverse reaction caused by antibiotics, shorten the treatment time and improve the quality of life of patients.