CAJ | 학술논문

目的：探讨药物干预对高龄老人早期正常眼压性青光眼(NTG)的预后影响。方法：对18例(36眼)早期NTG患者随机分为对照组8例(16眼),不予药物治疗，治疗组10例(20眼)，给予常规抗青光眼药物治疗。随访18月，记录患者视力、眼压、视野及眼底情况并进行分析。结果：随访18月，对照组视力较用药前下降，视野旁中心暗点范围扩大，杯盘比值上升，眼压差异无统计学意义。治疗组视力较用药前提高，眼压明显下降，13眼视野旁中心暗点范围缩小或消失，杯盘比值无变化。结论：NTG可导致视功能进行性恶化，尽早药物干预可控制病情，改善预后。
목적：탐토약물간예대고령노인조기정상안압성청광안(NTG)적예후영향。방법：대18례(36안)조기NTG환자수궤분위대조조8례(16안),불여약물치료，치료조10례(20안)，급여상규항청광안약물치료。수방18월，기록환자시력、안압、시야급안저정황병진행분석。결과：수방18월，대조조시력교용약전하강，시야방중심암점범위확대，배반비치상승，안압차이무통계학의의。치료조시력교용약전제고，안압명현하강，13안시야방중심암점범위축소혹소실，배반비치무변화。결론：NTG가도치시공능진행성악화，진조약물간예가공제병정，개선예후。
Objective To investgate the effect of drug intervention on the prognosis of early normal tension glaucoma(NTG) for aged patients. Methods Eighteen cases (36 eyes) with early NTG were randomly divided into treatment group 10 cases (20 eyes)and control group 8 cases (16 eyes). No treatment was given to the control group. The treatment group was given conventional anti-glaucoma drug. The visual acuity, intraocular pressure, funds and visual field were observed and analyzed. All cases were followed up for 18 months. Results After 18 months follow-up, in control group, the visual acuity was significantly decreased, intraocular pressure was main-tained in normal ranges and no statistically significant, the ratio of cup to disc was increased, and the ranges of paracentral scotoma in the visual field defect were enlarged. In the treatment group, the visual acuity was in-creased, intraocular pressure was significantly decreased, the ratio of cup to disc had no change, and the ranges of paracentral scotoma in the visual field defect were lessened or disappeared in 13 cases. Conclusion The visual function of NTG will lead to progressive deterioration without medical intervention, and the disease can be con-troled and the prognosis can be improved if the drug intervention is conducted as soon as possible in early NTG.