CAJ | 학술논문

目的：评估18 F氟脱氧葡萄糖正电子发射断层显像（18 F-FDG PET/CT ）在诊断宫颈癌原发灶和盆腔淋巴结转移中的价值。方法回顾性分析57例宫颈癌患者病历资料，将治疗前18 F-FDG PET/CT 检查结果与术后病理结果进行比较。结果宫颈癌原发灶18 F-FDG PET/CT 检查阳性55例，阴性2例，诊断敏感度96．5％（55/57）。22例经手术治疗患者中，9例（9/22，40．9％）经手术病理证实盆腔淋巴结转移。18 F-FDG PET/CT 诊断宫颈癌盆腔淋巴结转移的敏感度、特异度、准确度、阳性预测值和阴性预测值分别为66．7％（6/9）、92．3％（12/13）、81．8％（18/22）、85．7％（6/7）、80．0％（12/15）。结论18 F-FDG PET/CT诊断宫颈癌原发灶具有极高的敏感度，能有效地检出宫颈癌原发灶；诊断宫颈癌盆腔淋巴结转移特异度较高，但敏感度一般，特别是短径＜1．0 cm淋巴结。
목적：평고18 F불탈양포도당정전자발사단층현상（18 F-FDG PET/CT ）재진단궁경암원발조화분강림파결전이중적개치。방법회고성분석57례궁경암환자병력자료，장치료전18 F-FDG PET/CT 검사결과여술후병리결과진행비교。결과궁경암원발조18 F-FDG PET/CT 검사양성55례，음성2례，진단민감도96．5％（55/57）。22례경수술치료환자중，9례（9/22，40．9％）경수술병리증실분강림파결전이。18 F-FDG PET/CT 진단궁경암분강림파결전이적민감도、특이도、준학도、양성예측치화음성예측치분별위66．7％（6/9）、92．3％（12/13）、81．8％（18/22）、85．7％（6/7）、80．0％（12/15）。결론18 F-FDG PET/CT진단궁경암원발조구유겁고적민감도，능유효지검출궁경암원발조；진단궁경암분강림파결전이특이도교고，단민감도일반，특별시단경＜1．0 cm림파결。
Objective To evaluate the clinical value of 18 F-fluorodeoxyglucose positron emission tomography (18 F-FDG PET/CT ) in the diagnosis of primary cervical cancer and pelvic lymph node metasta-sis . Methods The clinical data of 57 patients with cervical cancer were retrospectively analyzed . All patients underwent 18 F-FDG PET/CT scanning pretherapy . The diagnostic results of 18 F-FDG PET/CT were compared with postoperative pathological findings . Results Of the 57 patients with pathologically confirmed cervical cancer ,18 F-FDG PET/CT was positive in 55(55/57 ,96 .5% )patients and negative in 2 (2/57 ,3 .5% )patients in the primary lesion . The sensitivity of 18 F-FDG PET/CT was 96 .5% (55/57) . In with 22 patients who underwent surgical treatment ,9(9/22 ,40 .9% ) were confirmed pelvic lymph node metastasis by postoperative pathological findings . T he sensitivity ,specificity ,accuracy ,positive predic-tive value and negative predictive value of 18 F-FDG PET/CT in detect the pelvic lymph node metastasis w ere 66 .7% (6/9 ) ,92 .3% (12/13 ) ,81 .8% (18/22 ) ,85 .7% (6/7 ) ,80 .0% (12/15 ) ,respectively . Conclusions 18 F-FDG PET/CT has a high sensitivity in diagnosis of the primary lesion of cervical cancer , it can effectively detect primary tumors ;in pelvic lymph node metastasis ,the diagnosis specificity of this method is high ,but sensitivity is moderate ,especially the short diameter <1 .0 cm lymph nodes .