中华临床医师杂志(电子版)
中華臨床醫師雜誌(電子版)
중화림상의사잡지(전자판)
CHINESE JOURNAL OF CLINICIANS(ELECTRONIC VERSION)
2013年
22期
10066-10069
,共4页
妊娠率%年龄因素%囊胚%可移植胚胎率
妊娠率%年齡因素%囊胚%可移植胚胎率
임신솔%년령인소%낭배%가이식배태솔
Pregnancy rate%Age factors%Blastula%Embryo transfer rate
目的:探讨累计妊娠率的相关因素。方法选取本生殖中心2010年11月至2013年6月完成一次取卵周期的患者为研究对象,比较年龄、获 MⅡ卵比率、受精率、正常受精率、囊胚形成率和可移植胚胎率与累计临床妊娠率的相关性,并对相关因素进行深入探讨。结果年龄、囊胚生成率和可移植胚胎率与累计临床妊娠率相关。其中,30岁以下组累计妊娠率明显高于30岁以上组(卡方检验P<0.05)。有囊胚生成组累计妊娠率显著高于无囊胚生成组(卡方检验P<0.05)。可移植胚胎率(ETR)>75%组累计妊娠率高于50%<ETR≤75%组,更高于ETR≤50%组,各组间妊娠结局均有差异(卡方检验P<0.05)。结论年龄、囊胚生成率和可移植胚胎率与累计妊娠率相关。30岁以下具有较高的临床妊娠率;非优质胚胎囊胚培养在预测累计妊娠率上有一定价值;可移植胚胎率在一次取卵周期累计妊娠率中有强提示作用。
目的:探討纍計妊娠率的相關因素。方法選取本生殖中心2010年11月至2013年6月完成一次取卵週期的患者為研究對象,比較年齡、穫 MⅡ卵比率、受精率、正常受精率、囊胚形成率和可移植胚胎率與纍計臨床妊娠率的相關性,併對相關因素進行深入探討。結果年齡、囊胚生成率和可移植胚胎率與纍計臨床妊娠率相關。其中,30歲以下組纍計妊娠率明顯高于30歲以上組(卡方檢驗P<0.05)。有囊胚生成組纍計妊娠率顯著高于無囊胚生成組(卡方檢驗P<0.05)。可移植胚胎率(ETR)>75%組纍計妊娠率高于50%<ETR≤75%組,更高于ETR≤50%組,各組間妊娠結跼均有差異(卡方檢驗P<0.05)。結論年齡、囊胚生成率和可移植胚胎率與纍計妊娠率相關。30歲以下具有較高的臨床妊娠率;非優質胚胎囊胚培養在預測纍計妊娠率上有一定價值;可移植胚胎率在一次取卵週期纍計妊娠率中有彊提示作用。
목적:탐토루계임신솔적상관인소。방법선취본생식중심2010년11월지2013년6월완성일차취란주기적환자위연구대상,비교년령、획 MⅡ란비솔、수정솔、정상수정솔、낭배형성솔화가이식배태솔여루계림상임신솔적상관성,병대상관인소진행심입탐토。결과년령、낭배생성솔화가이식배태솔여루계림상임신솔상관。기중,30세이하조루계임신솔명현고우30세이상조(잡방검험P<0.05)。유낭배생성조루계임신솔현저고우무낭배생성조(잡방검험P<0.05)。가이식배태솔(ETR)>75%조루계임신솔고우50%<ETR≤75%조,경고우ETR≤50%조,각조간임신결국균유차이(잡방검험P<0.05)。결론년령、낭배생성솔화가이식배태솔여루계임신솔상관。30세이하구유교고적림상임신솔;비우질배태낭배배양재예측루계임신솔상유일정개치;가이식배태솔재일차취란주기루계임신솔중유강제시작용。
Objective To explore IVF productivity rate(or cumulative pregnancy rate per collection cycle) correlated factors. Methods Patients completed an oocyte retrieval cycle in our reproductive medicine center from November, 2010 to June, 2013 were chose as the study objects. The correlation between age, MII oocyte ratio, fertilization rate, normal fertilization rate, blastocyst formation rate(BFR), embryo transfer rate(ETR) and productivity rate were analyzed. And the relevant factors were explored further. Results Age, BFR and ETR were related with productivity rate. Productivity rate of less than 30 years old group was higher than more than 30 years old group(chi-square test, P<0.05). Productivity rate of blastocyst formed group was higher than no blastocyst formed group(chi-square test, P<0.05). The pregnancy outcome among ETR>75%group, 50%<ETR≤75% group and ETR≤50% group were different(chi-square test, P<0.05). Conclusions Age, blastocyst formation rate and embryo transfer rate were correlated with productivity rate. Less than 30 years had higher clinical pregnancy rate. Blastocyst culture of poor quality embryo has certain value in the prediction of productivity rate. Embryos transfer rate has strong implications in prediction of productivity rate.