CAJ | 학술논문

目的：分析体素内无规则运动核磁成像（intravoxel incoherent motion MR imaging，IVIM-MRI）参数与病理诊断的相关性，探讨其在诊断、评估前列腺癌的恶性程度、预后的应用价值。方法分析21例前列腺癌患者IVIM参数弥散系数D及灌注因子f，结合病理结果对比良性增生组织与肿瘤组织及中高危组与低危组中之间的区别。结果弥散系数D及灌注因子f （排除b=800 s/mm2）在良、恶性组织中差异均具有统计学意义（P＜0.05），同时，弥散系数D在中高危组与低危组之间差异也具统计学意义（P＜0.05）。结论 IVIM技术有助于前列腺癌的诊断；弥散系数D值有助于对前列腺癌恶性程度的预估。
목적：분석체소내무규칙운동핵자성상（intravoxel incoherent motion MR imaging，IVIM-MRI）삼수여병리진단적상관성，탐토기재진단、평고전렬선암적악성정도、예후적응용개치。방법분석21례전렬선암환자IVIM삼수미산계수D급관주인자f，결합병리결과대비량성증생조직여종류조직급중고위조여저위조중지간적구별。결과미산계수D급관주인자f （배제b=800 s/mm2）재량、악성조직중차이균구유통계학의의（P＜0.05），동시，미산계수D재중고위조여저위조지간차이야구통계학의의（P＜0.05）。결론 IVIM기술유조우전렬선암적진단；미산계수D치유조우대전렬선암악성정도적예고。
Objective To evaluate the value of intravoxel incoherent motion MR imaging diffusion coefficients (D) and perfusion fractions (f ) in the diagnosis of prostate cancer. Methods The clinical and imaging data of 21 patients with prostatic cancer were analyzed retrospectively, including the D values and the f values of the different pathological pattern and the different levels of malignancy. Results There were significant difference in D values and f values (exclude b=800s/mm2) between the normal and tumor tissues(P<0.05). But, between the different levels of malignancy, only the D values had statistical difference(P<0.05). Conclusion IVIM shows some advantages in the differential diagnosis of prostatic cancer and accurate quantification of D value will be helpful to determine tumor malignancy.