浙江临床医学
浙江臨床醫學
절강림상의학
ZHEJIANG CLINICAL MEDICAL JOURNAL
2014年
1期
6-7,8
,共3页
糖化血红蛋白%冠心病%Gensini积分%心血管造影术(CAG)
糖化血紅蛋白%冠心病%Gensini積分%心血管造影術(CAG)
당화혈홍단백%관심병%Gensini적분%심혈관조영술(CAG)
Hemoglobin A1c%Number of diseased coronary branches%Gensini score%Coronary angiography
目的：探讨糖化血红蛋白（HbA1c）与冠状动脉病变（简称冠脉病变）程度的相关性及临床意义。方法将因有心绞痛病史或心电图有心肌缺血表现而进行冠脉造影的254例患者根据其HbAlc水平分组。A组：HbA1c<7.0%（n=102）；B组：7.0%≤HbA1c<9.0%（n=95）；C组：HbA1c≥9.0%（n=57）。据冠脉造影结果，评价HbA1c水平与冠心病，冠脉病变支数及冠脉病变程度积分（Gensini积分）之间的相关性。结果3组间BMI、WC、FPG、TG、TC、UA等水平差异均有统计学意义（P<0.05）。随着HbA1c水平的升高，冠心病患病率升高（P<0.05）。HbA1c水平与冠脉病变支数及病变程度积分显著相关（r=0.243，P<0.01；r=0.248，P<0.01）。结论随HbA1c水平升高，冠脉病变逐渐复杂且严重，故有效控制血糖水平对预防冠心病及冠心病进展甚为重要。
目的：探討糖化血紅蛋白（HbA1c）與冠狀動脈病變（簡稱冠脈病變）程度的相關性及臨床意義。方法將因有心絞痛病史或心電圖有心肌缺血錶現而進行冠脈造影的254例患者根據其HbAlc水平分組。A組：HbA1c<7.0%（n=102）；B組：7.0%≤HbA1c<9.0%（n=95）；C組：HbA1c≥9.0%（n=57）。據冠脈造影結果，評價HbA1c水平與冠心病，冠脈病變支數及冠脈病變程度積分（Gensini積分）之間的相關性。結果3組間BMI、WC、FPG、TG、TC、UA等水平差異均有統計學意義（P<0.05）。隨著HbA1c水平的升高，冠心病患病率升高（P<0.05）。HbA1c水平與冠脈病變支數及病變程度積分顯著相關（r=0.243，P<0.01；r=0.248，P<0.01）。結論隨HbA1c水平升高，冠脈病變逐漸複雜且嚴重，故有效控製血糖水平對預防冠心病及冠心病進展甚為重要。
목적：탐토당화혈홍단백（HbA1c）여관상동맥병변（간칭관맥병변）정도적상관성급림상의의。방법장인유심교통병사혹심전도유심기결혈표현이진행관맥조영적254례환자근거기HbAlc수평분조。A조：HbA1c<7.0%（n=102）；B조：7.0%≤HbA1c<9.0%（n=95）；C조：HbA1c≥9.0%（n=57）。거관맥조영결과，평개HbA1c수평여관심병，관맥병변지수급관맥병변정도적분（Gensini적분）지간적상관성。결과3조간BMI、WC、FPG、TG、TC、UA등수평차이균유통계학의의（P<0.05）。수착HbA1c수평적승고，관심병환병솔승고（P<0.05）。HbA1c수평여관맥병변지수급병변정도적분현저상관（r=0.243，P<0.01；r=0.248，P<0.01）。결론수HbA1c수평승고，관맥병변축점복잡차엄중，고유효공제혈당수평대예방관심병급관심병진전심위중요。
Objective To investigate the relationship between HbA1c level and severity of coronary artery disease. Methods A total of 254 patients with angina pectoris or myocardial ischemia in ECG were divided into three groups according to the level of HbA1c.one hundred and two patients were in group A with HbA1c<7.0%;ninety five patients in group B with 7.0%≤HbA1c<9.0%;fifty seven patients were in group C with HbA1c≥9.0%,theangiographic characteristics of coronary artery among them were analyzed and the Gensini score were compared between the there groups. Results The level of body mass index,waist circumference, fasting plasma glucose,total cholesterol,triglyceride,uric acid in three group were different,and the differences were significant. Along with the increased HbA1c level,theprevalence of coronary heart disease was significantly higher(P<0.05),the HbA1c level had a positive correlation with number of diseased coronary branches,Gensini score.(r=0.243,P<0.01;r=0.248,P<0.01). Conclusion HbA1c is an independent risk factor in patients with coronary artery disease,and well control of glucose is critical for the treatment of CHD.
