中国保健营养(中旬刊)
中國保健營養(中旬刊)
중국보건영양(중순간)
China Hwalth Care & nutrition
2013年
4期
3-4
,共2页
幽门螺杆菌%消化性溃疡%雷贝拉唑%奥美拉唑%左氧氟沙星%阿莫西林%克拉霉素%联合
幽門螺桿菌%消化性潰瘍%雷貝拉唑%奧美拉唑%左氧氟沙星%阿莫西林%剋拉黴素%聯閤
유문라간균%소화성궤양%뢰패랍서%오미랍서%좌양불사성%아막서림%극랍매소%연합
HP%Peptic ulcer%Rabeprazole%Omeprazole%Left-ofloxacin%Amoxicillin%Clarithromycin%Joint
目的:探讨4药联合根治幽门螺杆菌阳性消化性溃疡的临床疗效。方法:将162例患者随机分为对照组81例和治疗组81例,对照组患者使用奥美拉唑、阿莫西林、克拉霉素3药联合口服;治疗组使用雷贝拉唑、枸橼酸铋钾胶囊、左氧氟沙星、阿莫西林4药联合口服。观察治疗前后的症状变化,不良反应,记录溃疡愈合、HP根除及药物不良反应发生情况。结果:治疗组疼痛消失时间、药物不良反应明显低于对照组,服药2周后症状消失率91.4%、HP根治率90.1%、溃疡愈合率92.6%,明显高于对照组的83.9%、80.2%、81.5%,组间比较(P﹤0.05),具有统计学意义。结论:使用雷贝拉唑、枸橼酸铋钾胶囊、左氧氟沙星、阿莫西林4药联合治疗消化性溃疡HP根治率高、溃疡愈合率高、患者耐受性好、不良反应少,值得临床推广使用。
目的:探討4藥聯閤根治幽門螺桿菌暘性消化性潰瘍的臨床療效。方法:將162例患者隨機分為對照組81例和治療組81例,對照組患者使用奧美拉唑、阿莫西林、剋拉黴素3藥聯閤口服;治療組使用雷貝拉唑、枸櫞痠鉍鉀膠囊、左氧氟沙星、阿莫西林4藥聯閤口服。觀察治療前後的癥狀變化,不良反應,記錄潰瘍愈閤、HP根除及藥物不良反應髮生情況。結果:治療組疼痛消失時間、藥物不良反應明顯低于對照組,服藥2週後癥狀消失率91.4%、HP根治率90.1%、潰瘍愈閤率92.6%,明顯高于對照組的83.9%、80.2%、81.5%,組間比較(P﹤0.05),具有統計學意義。結論:使用雷貝拉唑、枸櫞痠鉍鉀膠囊、左氧氟沙星、阿莫西林4藥聯閤治療消化性潰瘍HP根治率高、潰瘍愈閤率高、患者耐受性好、不良反應少,值得臨床推廣使用。
목적:탐토4약연합근치유문라간균양성소화성궤양적림상료효。방법:장162례환자수궤분위대조조81례화치료조81례,대조조환자사용오미랍서、아막서림、극랍매소3약연합구복;치료조사용뢰패랍서、구연산필갑효낭、좌양불사성、아막서림4약연합구복。관찰치료전후적증상변화,불량반응,기록궤양유합、HP근제급약물불량반응발생정황。결과:치료조동통소실시간、약물불량반응명현저우대조조,복약2주후증상소실솔91.4%、HP근치솔90.1%、궤양유합솔92.6%,명현고우대조조적83.9%、80.2%、81.5%,조간비교(P﹤0.05),구유통계학의의。결론:사용뢰패랍서、구연산필갑효낭、좌양불사성、아막서림4약연합치료소화성궤양HP근치솔고、궤양유합솔고、환자내수성호、불량반응소,치득림상추엄사용。
Objective:Explore 4 drugs cure Helicobacter pylori positive peptic ulcer:clinical observations. Methods:162 patients were randomly assigned to the control group and treatment group,81 of 81 cases,patients with control groups using omeprazole,amoxicillin,clarithromycin 3 oral drug treatment group using rabeprazole,bismuth potassium citrate capsules,left,ofloxacin,4 drug amoxicillin oral. Observation of changes of symptoms before and after treatment, side effects,adverse drug reactions records,HP eradication and ulcer healing. Results:Treatment groups it well,adverse drug reaction is typically lower than the control group,symptoms disappear after 2 weeks of taking radical resection rate rate 91.4%,HP 90.1%,ulcer healing rate cent,significantly higher than the control group,83.9%,81.5%,group comparison (p ﹤ 0.05),statistically significant. Conclusion:Using rabeprazole,bismuth potassium citrate capsules, left,ofloxacin,amoxicillin 4 HP high cure rates of drug treatment of peptic ulcer,ulcer healing rate high,less well tolerated and adverse reaction in patients with, and clinical use.