CAJ | 학술논문

目的：了解婴幼儿腹泻与轮状病毒感染的季节性及年龄段分布特点。方法2012年1～12月儿科门诊及住院1539例0～5岁腹泻患儿的新鲜粪便标本，采用A群轮状病毒诊断试剂盒检测标本中的A群轮状病毒抗原。结果1539份标本中轮状病毒检测阳性356例，阳性率为23.13％；12个月中11月份检出率最高，为45.87％，其次为12月份，为33.73％；高发年龄段为6月龄～1岁，检出率高达39.07％；男性患儿检出率为21.90％，女性患儿检出率为24.33％，两者无显著性差异（χ2＝1.142，P＞0.05）。结论 A群轮状病毒是引起小儿腹泻的主要病原体之一，高发季节为秋冬季，临床医生应重视对腹泻小儿的粪便轮状病毒检测，以便为临床早期诊断和治疗提供依据。
목적：료해영유인복사여륜상병독감염적계절성급년령단분포특점。방법2012년1～12월인과문진급주원1539례0～5세복사환인적신선분편표본，채용A군륜상병독진단시제합검측표본중적A군륜상병독항원。결과1539빈표본중륜상병독검측양성356례，양성솔위23.13％；12개월중11월빈검출솔최고，위45.87％，기차위12월빈，위33.73％；고발년령단위6월령～1세，검출솔고체39.07％；남성환인검출솔위21.90％，녀성환인검출솔위24.33％，량자무현저성차이（χ2＝1.142，P＞0.05）。결론 A군륜상병독시인기소인복사적주요병원체지일，고발계절위추동계，림상의생응중시대복사소인적분편륜상병독검측，이편위림상조기진단화치료제공의거。
Objective To study the seasonal , age features of rotavirus infection in diarrhea infants.Methods Total-ly 1539 stool specimens were collected from the children aged from 0~5 years with diarrhea.Group A rotavirus antigen was detected by group A rotavirus diagnostic kit.Results Rotavirus antigen was detected in 356 out of 1539 specimens, with a positive rate of 23.13%;November was the peak season , with a positive rate of 45.87%, then followed by De-cember , with a positive rate of 33.73%;The susceptible age was from 6 months to 1 years old, the positive rate of which was 39.07%;The rotavirus positive rate in males was 21.90%and 24.33%in females (χ2 =1.142 , P >0.05 ).Con-clusions Rotavirus is one of the main pathogens which cause the infant diarrhea , the diarrhea caused by the group A ro-tavirus in infants and young children mainly occurs in autumn and winter , attention should be paid to the detection of pathogen for diarrhea infants to provide the basis for the clinical diagnosis and symptomatic therapy .