CAJ | 학술논문

以奎宁分子为模板，甲基丙烯酸( MAA)为功能单体，乙二醇二甲基丙烯酸酯( EDMA)为交联剂，二硫代四乙基秋兰姆( TED)为活性/可控引发剂，将可逆加成-断裂链转移自由基聚合与沉淀聚合相结合，制备微米级的球形奎宁分子印迹聚合物。并用扫描电镜和激光粒度扫描对聚合物粒子进行表征，结果显示，活性/可控聚合制备的分子印迹聚合物呈均匀的球形，其平均粒径最大可达2．3μm。对不同底物的结合实验表明，与传统沉淀聚合物相比，该分子印迹聚合物表现出更高的络合容量和分子选择性。
이규저분자위모판，갑기병희산( MAA)위공능단체，을이순이갑기병희산지( EDMA)위교련제，이류대사을기추란모( TED)위활성/가공인발제，장가역가성-단렬련전이자유기취합여침정취합상결합，제비미미급적구형규저분자인적취합물。병용소묘전경화격광립도소묘대취합물입자진행표정，결과현시，활성/가공취합제비적분자인적취합물정균균적구형，기평균립경최대가체2．3μm。대불동저물적결합실험표명，여전통침정취합물상비，해분자인적취합물표현출경고적락합용량화분자선택성。
The spherical molecularly imprinted polymers with micron-size were prepared by using quinine as template,methylacrylic acid( MAA) as functional monomer,ethylene glycol dimethacrylate( EDMA) as cross-linker and dithiotetraethylthiuram( TED) as the living/controlled initiator by combining reversible addition-fragmentation chain transfer radical polymerization with precipitation pol-ymerization. The polymeric particles were characterized by scanning electron microscopy and laser particle size analysis. The results show that the polymeric particles prepared by living/controlled polymerization present uniform spherical shape and its maximum av-erage diameter reach 2. 3 μm. The binding experiment towards different substrates indicates that the living/controlled molecularly imprinted polymer shows higher binding capacity and molecular selectivity than the traditional precipitation polymers.