华西口腔医学杂志
華西口腔醫學雜誌
화서구강의학잡지
WEST CHINA JOURNAL OF STOMATOLOGY
2014年
1期
32-35
,共4页
许鹏程%邓盟%周学东%李继遥%程磊%徐欣
許鵬程%鄧盟%週學東%李繼遙%程磊%徐訢
허붕정%산맹%주학동%리계요%정뢰%서흔
釉质早期龋%精氨酸牙膏%精氨酸%再矿化
釉質早期齲%精氨痠牙膏%精氨痠%再礦化
유질조기우%정안산아고%정안산%재광화
early enamel caries%arginine dentifrice%arginine%remineralization
目的： 研究精氨酸牙膏对人牙釉质早期龋的再矿化效果。方法 制备人牙釉质龋标本，随机分为3组：空白组（去离子水处理），对照组（普通市售含氟牙膏处理，含质量分数0.14%单氟磷酸钠），实验组（精氨酸牙膏处理，含质量分数0.14%单氟磷酸钠和8%精氨酸）。经体外pH循环10 d，测量pH循环前后各组样本的表面显微硬度，计算其差值；并通过偏光显微镜观察各组样本再矿化前后的形态学改变。pH循环结束后，脱矿处理2 h，测量其表面显微硬度，计算与pH循环前的差值，评估再矿化处理对釉质抗酸能力的影响。采用酸蚀法测定各组的氟摄入量。结果 与对照组和空白组比较，实验组釉质表面的显微硬度、抗酸能力，以及氟摄入量均明显升高。偏光显微镜下观察，实验组病损深度明显变浅，且有表层下再矿化条带，而空白组与对照组病损无明显变化。结论 精氨酸牙膏能有效促进人牙釉质龋表层及表层下再矿化，在早期龋的防治领域具有较大的临床应用前景。
目的： 研究精氨痠牙膏對人牙釉質早期齲的再礦化效果。方法 製備人牙釉質齲標本，隨機分為3組：空白組（去離子水處理），對照組（普通市售含氟牙膏處理，含質量分數0.14%單氟燐痠鈉），實驗組（精氨痠牙膏處理，含質量分數0.14%單氟燐痠鈉和8%精氨痠）。經體外pH循環10 d，測量pH循環前後各組樣本的錶麵顯微硬度，計算其差值；併通過偏光顯微鏡觀察各組樣本再礦化前後的形態學改變。pH循環結束後，脫礦處理2 h，測量其錶麵顯微硬度，計算與pH循環前的差值，評估再礦化處理對釉質抗痠能力的影響。採用痠蝕法測定各組的氟攝入量。結果 與對照組和空白組比較，實驗組釉質錶麵的顯微硬度、抗痠能力，以及氟攝入量均明顯升高。偏光顯微鏡下觀察，實驗組病損深度明顯變淺，且有錶層下再礦化條帶，而空白組與對照組病損無明顯變化。結論 精氨痠牙膏能有效促進人牙釉質齲錶層及錶層下再礦化，在早期齲的防治領域具有較大的臨床應用前景。
목적： 연구정안산아고대인아유질조기우적재광화효과。방법 제비인아유질우표본，수궤분위3조：공백조（거리자수처리），대조조（보통시수함불아고처리，함질량분수0.14%단불린산납），실험조（정안산아고처리，함질량분수0.14%단불린산납화8%정안산）。경체외pH순배10 d，측량pH순배전후각조양본적표면현미경도，계산기차치；병통과편광현미경관찰각조양본재광화전후적형태학개변。pH순배결속후，탈광처리2 h，측량기표면현미경도，계산여pH순배전적차치，평고재광화처리대유질항산능력적영향。채용산식법측정각조적불섭입량。결과 여대조조화공백조비교，실험조유질표면적현미경도、항산능력，이급불섭입량균명현승고。편광현미경하관찰，실험조병손심도명현변천，차유표층하재광화조대，이공백조여대조조병손무명현변화。결론 정안산아고능유효촉진인아유질우표층급표층하재광화，재조기우적방치영역구유교대적림상응용전경。
Objective To evaluate remineralization efficacy of an arginine containing dentifrice on initial enamel carious lesions in vitro. Methods Human enamel blocks with early lesions were prepared and randomly divided into three treatment groups: negative control group (distilled and deionized water), positive control group (fluoride containing dentifrice and 0.14% sodium monofluorophosphate), and test dentifrice group (8.0% arginine and 0.14% sodium monofluorophosphate). The lesions were subjected to a pH-cycling regime for 10 days. Surface enamel microhardness of the enamel blocks from each group was measured before and after pH cycling, and the surface microhardness recovery was calculated. Then, specimens were analyzed for enamel fluoride uptake (EFU) through acid etching method, after which they were treated in demineralization solution for a 2 h period of acid challenge. The other specimens were sectioned and examined through polarized light microscopy. Results In the test dentifrice group, microhardness recovery and EFU were significantly higher than those in the negative control and positive groups. The test dentifrice group was significantly resistant to the acid challenge compared with the other groups. Conspicuous remineralization of enamel subsurface lesions was observed under polarized light microscopy among samples treated with test dentifrice, whereas the control groups showed no significant changes on enamel subsurface lesions. Conclusion This study presents the potential superiority of Pro-Argin dentifrice over conventional fluoride dentifrice in promoting the remineralization of initial enamel lesions.
