中国医药导刊
中國醫藥導刊
중국의약도간
CHINESE JOURNAL OF MEDICAL GUIDE
2014年
2期
272-273
,共2页
瑞舒伐他汀%尼莫同%血管性认知障碍%MoCA
瑞舒伐他汀%尼莫同%血管性認知障礙%MoCA
서서벌타정%니막동%혈관성인지장애%MoCA
Rosuvastatin%Nimodipine%Vascular cognitive impairment%MoCA
目的：探讨瑞舒伐他汀联合尼莫同对血管性认知障碍(VCI)的临床疗效。方法：收集120例VCI患者，随机分为三组，每组各40例。尼莫同组单用该药物，联合组采用瑞舒伐他汀联合尼莫同，对照组不使用改善认知的药物，使用MoCA量表分别对三组患者治疗前和治疗后6个月进行测量。结果：与对照组比较，联合组与尼莫同组MoCA得分均有显著改善(P<0.01)，联合组MoCA得分及主要子项目得分高于尼莫同组(P<0.01)。结论：瑞舒伐他汀联合尼莫同对VCI患者的认知功能有较好的改善作用，二者可能具有协同效益。
目的：探討瑞舒伐他汀聯閤尼莫同對血管性認知障礙(VCI)的臨床療效。方法：收集120例VCI患者，隨機分為三組，每組各40例。尼莫同組單用該藥物，聯閤組採用瑞舒伐他汀聯閤尼莫同，對照組不使用改善認知的藥物，使用MoCA量錶分彆對三組患者治療前和治療後6箇月進行測量。結果：與對照組比較，聯閤組與尼莫同組MoCA得分均有顯著改善(P<0.01)，聯閤組MoCA得分及主要子項目得分高于尼莫同組(P<0.01)。結論：瑞舒伐他汀聯閤尼莫同對VCI患者的認知功能有較好的改善作用，二者可能具有協同效益。
목적：탐토서서벌타정연합니막동대혈관성인지장애(VCI)적림상료효。방법：수집120례VCI환자，수궤분위삼조，매조각40례。니막동조단용해약물，연합조채용서서벌타정연합니막동，대조조불사용개선인지적약물，사용MoCA량표분별대삼조환자치료전화치료후6개월진행측량。결과：여대조조비교，연합조여니막동조MoCA득분균유현저개선(P<0.01)，연합조MoCA득분급주요자항목득분고우니막동조(P<0.01)。결론：서서벌타정연합니막동대VCI환자적인지공능유교호적개선작용，이자가능구유협동효익。
Objective:To investigate the efficacy of rosuvastatin and nimodipine combination treatment for vascular cognitive impairment.Methods:120 patients with vascular cognitive impairment were randomly divided into 3 groups:Nimodipine Group(NG) treated with nimodipine only,Combination Group(Com G) treated with rosuvastatin and nimodipine,and Control Group(CG) treated without any medicine to improve vascular cognitive impairment.MoCA Scale of three groups was assessed and compared before and 6 months after treatment.Results:Comparing with CG,the MoCA Scale was improved markedly in NG and Com G(P<0.01).Furthermore,Com G had higher scores than NG in MoCA Scale,especially in some main item.Conclusion:Rosuvastatin and nimodipine can markedly and cooperatively improve the cognitive function of patients with vascular cognitive impairment.
