CAJ | 학술논문

目的：探讨苯磺酸左旋氨氯地平联合依那普利治疗原发性高血压的疗效和安全性。方法：将2011年6月~2013年2月期间本院收诊的原发性高血压患者随机分成两组,对照组和观察组各92例,对照组采用依那普利治疗,观察组采用苯磺酸左旋氨氯地平联合依那普利治疗。治疗前后对两组血压进行测量,比较疗效差异；同时对患者的肝肾功能进行检测,并统计不良反应发生率。结果：治疗4、12周后,观察组患者24hSBP和24hDBP均显著低于对照组,P<0.05。观察组患者显效率和总有效率均显著高于对照组,P<0.05。观察组不良反应发生率低于对照组,P>0.05。结论：苯磺酸左旋氨氯地平联合依那普利治疗原发性高血压疗效好,且安全性高。
목적：탐토분광산좌선안록지평연합의나보리치료원발성고혈압적료효화안전성。방법：장2011년6월~2013년2월기간본원수진적원발성고혈압환자수궤분성량조,대조조화관찰조각92례,대조조채용의나보리치료,관찰조채용분광산좌선안록지평연합의나보리치료。치료전후대량조혈압진행측량,비교료효차이；동시대환자적간신공능진행검측,병통계불량반응발생솔。결과：치료4、12주후,관찰조환자24hSBP화24hDBP균현저저우대조조,P<0.05。관찰조환자현효솔화총유효솔균현저고우대조조,P<0.05。관찰조불량반응발생솔저우대조조,P>0.05。결론：분광산좌선안록지평연합의나보리치료원발성고혈압료효호,차안전성고。
Objective:To evaluate the safety and efficacy of Levamlodipine and enalapril in the treatment of essential hypertension. Methods:Patients in our hospital diagnosed with essential hypertension during the period from June 2011 to February 2013 were randomly divided into two groups,the control group and the observation group,and 92 cases in each group. The control group was taken with enalapril treatment,and the observation group was treated with Levamlodipine besylate combined enalapril treatment.The blood pressure before and after treatment in the two groups was taken for measurement.The differences of the efficacy were compared.The function of liver and kidney at the same time was taken for detection.The incidence rate of adverse reaction was taken for statistics.Results:4,12 weeks after treatment,24h SBP and 24h DBP for patients in the observation group were significantly lower than those in the control group,P<0.05.The markedly effective rate and total effective rate in the observation group were significantly higher than those in the control group,P<0.05. The adverse reaction in the observation group was lower than that of the control group,P>0.05.Conclusion:The efficacy of levamlodipine and enalapril in the treatment of primary hypertension is good, and with higher safety.