CAJ | 학술논문

目的：观察宫腔镜下子宫内膜息肉电切术后应用屈螺酮炔雌醇片（优思明）治疗和预防子宫内膜息肉复发的临床疗效。方法子宫内膜息肉患者106例，随机分为2组，观察组53例，行子宫内膜息肉电切术后口服优思明治疗3个周期；对照组53例，行子宫内膜息肉电切术后未用药物治疗。随访6个月，观察比较2组治疗效果及复发情况。结果观察组月经改善的显效率、总有效率均高于对照组（73唵．6％ vs．45．3％，94．3％ vs．81．1％），差异有统计学意义（ P ＜0．05）；观察组子宫内膜息肉复发率为7．5％低于照组的24．5％（ P ＜0．05）。2组均未发生并发症，观察组于服药初期出现轻微恶心3例（5．7％），烦躁、易怒等情绪波动4例（7．5％），均自行缓解。结论宫腔镜下子宫内膜息肉电切术后联合应用优思明，可有效恢复正常月经，降低子宫内膜息肉复发率，不良反应少，值得临床推广。
목적：관찰궁강경하자궁내막식육전절술후응용굴라동결자순편（우사명）치료화예방자궁내막식육복발적림상료효。방법자궁내막식육환자106례，수궤분위2조，관찰조53례，행자궁내막식육전절술후구복우사명치료3개주기；대조조53례，행자궁내막식육전절술후미용약물치료。수방6개월，관찰비교2조치료효과급복발정황。결과관찰조월경개선적현효솔、총유효솔균고우대조조（73암．6％ vs．45．3％，94．3％ vs．81．1％），차이유통계학의의（ P ＜0．05）；관찰조자궁내막식육복발솔위7．5％저우조조적24．5％（ P ＜0．05）。2조균미발생병발증，관찰조우복약초기출현경미악심3례（5．7％），번조、역노등정서파동4례（7．5％），균자행완해。결론궁강경하자궁내막식육전절술후연합응용우사명，가유효회복정상월경，강저자궁내막식육복발솔，불량반응소，치득림상추엄。
Objective To observe effcicacy of polyp resection under hysteroscopic resection combined with applica -tion drospirenone ethinyl estradiol tablets (Yasmin) in treatment and prevention of endometrial polyp recurrence .Methods 106 patients with endometrial polyps were randomly divided into two groups , 53 cases in the observation group , received resec-tion of endometrial polyps and Yasmin oral treatment of three cycles;53 cases in the control group , only received resection of endometrial polyps .Follow-up of six months , the treatment effect and recurrence was observed and compared between the two groups.Results Significant improvement in the efficiency of the menstrual and the total effective rate were found in observa -tion group, which were better than the control group , the difference was statistically significant ( P <0.05) (73.6% vs. 45.3%, 94.3%vs.81.1%);Observation group's endometrial polyp recurrence rate was 7.5%, lower than the control group of 24.5%( P <0.05).Complications in the two groups did not occur , the observation group had mild nausea in 3 cases (5.7%), irritability, mood swings, irritability and other in 4 cases (7.5%), were spontaneous relieved.Conclusion Hyst-eroscopic endometrial polyp resection combined with Yasmin , which can effectively restore normal menstruation , reduce endo-metrial polyp recurrence rate , fewer adverse reactions , worthy of promotion .