中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2014年
11期
28-29,30
,共3页
妊娠期高血压疾病%凝血功能
妊娠期高血壓疾病%凝血功能
임신기고혈압질병%응혈공능
Pregnancy-induced hypertension%Coagulation
目的：探讨妊娠妇女凝血四项检测的临床意义。方法：应用法国STAGO全自动血凝分析仪测定859例妊娠妇女及200例正常非妊娠女性的PT、APTT、TT、FIB值，分成早、中、晚及临产妊娠四期和妊娠期高血压疾病、正常妊娠组进行比较分析。结果：随着妊娠时间延长，早期、中期至晚期妊娠的PT值呈缩短趋势，不同时间比较差异均有统计学意义（P<0.05）。晚期与临产期PT值比较差异无统计学意义（P>0.05）；随着妊娠时间的延长， APTT值呈缩短趋势，早期组与中期组比较差异有统计学意义（P<0.05），其他妊娠期APTT值比较差异均无统计学意义（P>0.05）。妊娠四个时期的TT值比较差异均无统计学意义（P>0.05）。早期、中期至晚期妊娠的FIB值比较差异均无统计学意义（P>0.05）。临产期FIB值明显升高，与其他各组比较差异均有统计学意义（P<0.05）。妊娠期高血压疾病组和正常妊娠组的PT、APTT、TT值比非妊娠组明显降低，FIB值明显升高，比较差异均有统计学意义（P<0.05）。妊娠期高血压疾病组的PT、APTT、TT值比正常妊娠组明显降低，FIB值明显升高，两组比较差异均有统计学意义（P<0.05）。结论：密切监测妊娠妇女的凝血四项变化，对预防血栓栓塞疾病和孕妇分娩过程中及产后大出血导致急性DIC的发生具有重要意义。
目的：探討妊娠婦女凝血四項檢測的臨床意義。方法：應用法國STAGO全自動血凝分析儀測定859例妊娠婦女及200例正常非妊娠女性的PT、APTT、TT、FIB值，分成早、中、晚及臨產妊娠四期和妊娠期高血壓疾病、正常妊娠組進行比較分析。結果：隨著妊娠時間延長，早期、中期至晚期妊娠的PT值呈縮短趨勢，不同時間比較差異均有統計學意義（P<0.05）。晚期與臨產期PT值比較差異無統計學意義（P>0.05）；隨著妊娠時間的延長， APTT值呈縮短趨勢，早期組與中期組比較差異有統計學意義（P<0.05），其他妊娠期APTT值比較差異均無統計學意義（P>0.05）。妊娠四箇時期的TT值比較差異均無統計學意義（P>0.05）。早期、中期至晚期妊娠的FIB值比較差異均無統計學意義（P>0.05）。臨產期FIB值明顯升高，與其他各組比較差異均有統計學意義（P<0.05）。妊娠期高血壓疾病組和正常妊娠組的PT、APTT、TT值比非妊娠組明顯降低，FIB值明顯升高，比較差異均有統計學意義（P<0.05）。妊娠期高血壓疾病組的PT、APTT、TT值比正常妊娠組明顯降低，FIB值明顯升高，兩組比較差異均有統計學意義（P<0.05）。結論：密切鑑測妊娠婦女的凝血四項變化，對預防血栓栓塞疾病和孕婦分娩過程中及產後大齣血導緻急性DIC的髮生具有重要意義。
목적：탐토임신부녀응혈사항검측적림상의의。방법：응용법국STAGO전자동혈응분석의측정859례임신부녀급200례정상비임신녀성적PT、APTT、TT、FIB치，분성조、중、만급임산임신사기화임신기고혈압질병、정상임신조진행비교분석。결과：수착임신시간연장，조기、중기지만기임신적PT치정축단추세，불동시간비교차이균유통계학의의（P<0.05）。만기여임산기PT치비교차이무통계학의의（P>0.05）；수착임신시간적연장， APTT치정축단추세，조기조여중기조비교차이유통계학의의（P<0.05），기타임신기APTT치비교차이균무통계학의의（P>0.05）。임신사개시기적TT치비교차이균무통계학의의（P>0.05）。조기、중기지만기임신적FIB치비교차이균무통계학의의（P>0.05）。임산기FIB치명현승고，여기타각조비교차이균유통계학의의（P<0.05）。임신기고혈압질병조화정상임신조적PT、APTT、TT치비비임신조명현강저，FIB치명현승고，비교차이균유통계학의의（P<0.05）。임신기고혈압질병조적PT、APTT、TT치비정상임신조명현강저，FIB치명현승고，량조비교차이균유통계학의의（P<0.05）。결론：밀절감측임신부녀적응혈사항변화，대예방혈전전새질병화잉부분면과정중급산후대출혈도치급성DIC적발생구유중요의의。
Objective:To investigate the clinical significance of coagulation testing in pregnant women. Method:PT,APTT,TT,FIB of 859 pregnant women and 200 normal non-pregnant women were analyzed by STAGO automated coagulation. 859 cases were divided into early,middle,late pregnancy and labor during pregnancy. 859 cases also were divided into pregnancy-induced hypertension and normal pregnancy group. Result:As a result of pregnancy time,PT value of early,mid-to late pregnancy was significantly shorter,and the difference were all statistically significant(P<0.05). APTT values of the early and mid-pregnancy was significantly shorter,and the difference were all statistically significant(P<0.05). TT values was no significant difference,and the difference were statistically significant(P<0.05). FIB values of labor during pregnancy was significantly increased,and the difference were statistically significant(P<0.05). PT,APTT,TT values of pregnancy-induced hypertension and normal pregnancy group was significantly lower than non-pregnant group while FIB values was significantly increased,and the difference were all statistically significant(P<0.05). PT,APTT,TT values of pregnancy-induced hypertension group was significantly lower than the normal pregnancy group,and the difference were all statistically significant(P<0.05). while FIB was significantly increased(P<0.05). Conclusion:Coagulation changes are close monitored in pregnant women for the prevention of thromboembolic disease and acute DIC occurs of pregnant women during childbirth and postpartum hemorrhage.
