CAJ | 학술논문

目的：探讨无创正压通气治疗慢性阻塞性肺病急性加重期早期的临床疗效。方法：选择180例慢性阻塞性肺病急性加重期早期患者，随机分为研究组与对照组，对照组给予止咳、平喘、化痰、吸氧、抗感染等一系列常规治疗，研究组在此基础之上给予无创正压通气治疗。结果：治疗1周后，两组患者的呼吸频率、心率、平均动脉压等基本情况均有所改善，而研究组的改善情况明显好于对照组（P<0.01）；两组患者的PaO2水平均有所上升，PaCO2水平均所有下降，而研究组患者两种指标水平的变化明显大于对照组（P<0.01）。结论：采用无创正压通气方法治疗慢性阻塞性肺病急性加重期早期的临床疗效较为显著，适合临床推广应用。
목적：탐토무창정압통기치료만성조새성폐병급성가중기조기적림상료효。방법：선택180례만성조새성폐병급성가중기조기환자，수궤분위연구조여대조조，대조조급여지해、평천、화담、흡양、항감염등일계렬상규치료，연구조재차기출지상급여무창정압통기치료。결과：치료1주후，량조환자적호흡빈솔、심솔、평균동맥압등기본정황균유소개선，이연구조적개선정황명현호우대조조（P<0.01）；량조환자적PaO2수평균유소상승，PaCO2수평균소유하강，이연구조환자량충지표수평적변화명현대우대조조（P<0.01）。결론：채용무창정압통기방법치료만성조새성폐병급성가중기조기적림상료효교위현저，괄합림상추엄응용。
Objective:To investigate clinical effect of noninvasive positive pressure ventilation in treatment of acute exacerbation early stage of chronic obstructive pulmonary disease. Method:180 patients with exacerbation early stage of chronic obstructive pulmonary disease were divided into the control group and the research group,the control group were treated by cough,asthma,phlegm,oxygen,antibiotics and a series of conventional treatment,the research group were treated by noninvasive positive pressure ventilation on the basis of the control group.Result:After treatment for one week, the respiratory rate,heart rate,mean arterial pressure of the research group were significantly better than that of the control group(P<0.01). The changes of the PaO2 level and PaCO2 level of the research group were significantly bigger than that of the control group(P<0.01).Conclusion:The clinical efficacy of using noninvasive positive pressure ventilation method for the treatment of chronic obstructive pulmonary disease is more significant.