中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2014年
11期
45-46
,共2页
不育症%夫精人工授精%DNA完整性%临床妊娠率
不育癥%伕精人工授精%DNA完整性%臨床妊娠率
불육증%부정인공수정%DNA완정성%림상임신솔
Infertility%AIH%DNA integrity%Clinical pregnancy
目的：研究精子DNA完整性对夫精人工授精妊娠结局的影响。方法：选取2011年1月-2013年1月在本院收治的111例男性不育症患者作为研究对象，根据精子DNA完整性将其分为A组（精子DNA完整性<30%）34例、B组（30%<精子DNA完整性<60%）42例以及C组（精子DNA完整性≥60%）35例，观察三精子质量及人工授精后的妊娠结局。结果：B、C组的临床妊娠率、精子总数、前向运动精子率均明显高于A组，差异均有统计学意义（P<0.05）。虽然C组的生化妊娠率、临床妊娠率、精子总数、前向运动精子率高于B组，但仅精子总数、前向运动精子率差异有统计学意义（P<0.05）。三组患者的临床妊娠率以及精子数目、前向运动精子率均为A组<B组<C组。结论：精子DNA完整性与人工授精妊娠结局密切相关，DNA完整性越好，精子质量越好，妊娠率越高。
目的：研究精子DNA完整性對伕精人工授精妊娠結跼的影響。方法：選取2011年1月-2013年1月在本院收治的111例男性不育癥患者作為研究對象，根據精子DNA完整性將其分為A組（精子DNA完整性<30%）34例、B組（30%<精子DNA完整性<60%）42例以及C組（精子DNA完整性≥60%）35例，觀察三精子質量及人工授精後的妊娠結跼。結果：B、C組的臨床妊娠率、精子總數、前嚮運動精子率均明顯高于A組，差異均有統計學意義（P<0.05）。雖然C組的生化妊娠率、臨床妊娠率、精子總數、前嚮運動精子率高于B組，但僅精子總數、前嚮運動精子率差異有統計學意義（P<0.05）。三組患者的臨床妊娠率以及精子數目、前嚮運動精子率均為A組<B組<C組。結論：精子DNA完整性與人工授精妊娠結跼密切相關，DNA完整性越好，精子質量越好，妊娠率越高。
목적：연구정자DNA완정성대부정인공수정임신결국적영향。방법：선취2011년1월-2013년1월재본원수치적111례남성불육증환자작위연구대상，근거정자DNA완정성장기분위A조（정자DNA완정성<30%）34례、B조（30%<정자DNA완정성<60%）42례이급C조（정자DNA완정성≥60%）35례，관찰삼정자질량급인공수정후적임신결국。결과：B、C조적림상임신솔、정자총수、전향운동정자솔균명현고우A조，차이균유통계학의의（P<0.05）。수연C조적생화임신솔、림상임신솔、정자총수、전향운동정자솔고우B조，단부정자총수、전향운동정자솔차이유통계학의의（P<0.05）。삼조환자적림상임신솔이급정자수목、전향운동정자솔균위A조<B조<C조。결론：정자DNA완정성여인공수정임신결국밀절상관，DNA완정성월호，정자질량월호，임신솔월고。
Objective:To study the effects of sperm DNA integrity on pregnancy outcome for AIH.Method:111 patients with male infertility were selected as research objects in our hospital from January 2011 to January 2013,according to the sperm DNA integrity patients were divided into the group A(sperm DNA integrity<30%)for 34 cases,the group B (30%<sperm DNA integrity<60%)for 42 cases and the group C(sperm DNA integrity≥60%)for 35 cases,sperm quality and pregnancy outcome of the three groups were observed after artificial insemination.Result:Clinical pregnancy rate,the total number of sperm,the rate of forward movement of sperm in the group B and group C were significantly higher than those in the group A,the differences were statistically significant(P<0.05).The rate of biochemical pregnancy,clinical pregnancy,the total number of sperm and the rate of forward movement of sperm in group C was higher than those in the group B,but there were statistically significant only about the total number of sperm and the rate of forward movement of sperm(P<0.05).The clinical pregnancy,the number of sperm,the rate of forward movement of sperm in the three groups was that:Group A<Group B<group C.Conclusion:The sperm DNA integrity is closely related to pregnancy outcomes after artificial insemination.DNA integrity is higher,the quality of sperm is better,the pregnancy rate is higher.
