CAJ | 학술논문

水凝胶是一种高含水量的三维网状聚合物,广泛应用于各个领域,但力学性能较差的特点限制了其在生物医用领域的应用。因此,如何提高水凝胶的力学强度成为国内外专家学者研究的重点。本文主要介绍了几种新型高强度水凝胶的合成及研究进展,包括滑动水凝胶、双网络水凝胶、复合水凝胶以及其它水凝胶,详细分析了影响这些水凝胶力学性能的因素。指出研制具有生物相容性、可生物降解、可注射、可负载活性因子并且具备良好的力学性能水凝胶是今后的研究方向。
수응효시일충고함수량적삼유망상취합물,엄범응용우각개영역,단역학성능교차적특점한제료기재생물의용영역적응용。인차,여하제고수응효적역학강도성위국내외전가학자연구적중점。본문주요개소료궤충신형고강도수응효적합성급연구진전,포괄활동수응효、쌍망락수응효、복합수응효이급기타수응효,상세분석료영향저사수응효역학성능적인소。지출연제구유생물상용성、가생물강해、가주사、가부재활성인자병차구비량호적역학성능수응효시금후적연구방향。
Hydrogels are there-dimensional polymer network in which the voids are filled with water. Hydrogels have been widely used in various fields including biomedical engineering. However, they have very limited applicability due to their poor mechanical strength. Therefore, many efforts have been focused on the enhancement of mechanical properties of hydrogels. This review mainly introduces some novel high strength hydrogels, such as slide-ring hydrogels, double network hydrogels, composite hydrogels and others and analyzes the factors affecting mechanical properties of hydrogels. Biocompatible, degradable, injectable, loading growth factor and high strength hydrogels as major research directions.