药物不良反应杂志
藥物不良反應雜誌
약물불량반응잡지
ADVERSE DRUG REACTIONS JOURNAL
2014年
3期
176-177
,共2页
李英%徐峥%张海英%冯婉玉%公丕花
李英%徐崢%張海英%馮婉玉%公丕花
리영%서쟁%장해영%풍완옥%공비화
阿奇霉素%房室传导阻滞
阿奇黴素%房室傳導阻滯
아기매소%방실전도조체
Azithromycin%Atrioventricular block
1例86岁女性患者因肺部感染静脉滴注头孢曲松钠2.0 g(1次/d)、阿奇霉素0.5 g (1次/d)和盐酸氨溴索30 mg(2次/d)。第4次静脉滴注阿奇霉素约30 min时,患者突然出现胸闷、憋气。心电图示Ⅲ度房室传导阻滞。立即停止药物输注,给予吸氧。1h后,患者胸闷、憋气消失。5h 后复测心电图示窦性心律。未再应用阿奇霉素,患者未再出现类似症状。
1例86歲女性患者因肺部感染靜脈滴註頭孢麯鬆鈉2.0 g(1次/d)、阿奇黴素0.5 g (1次/d)和鹽痠氨溴索30 mg(2次/d)。第4次靜脈滴註阿奇黴素約30 min時,患者突然齣現胸悶、憋氣。心電圖示Ⅲ度房室傳導阻滯。立即停止藥物輸註,給予吸氧。1h後,患者胸悶、憋氣消失。5h 後複測心電圖示竇性心律。未再應用阿奇黴素,患者未再齣現類似癥狀。
1례86세녀성환자인폐부감염정맥적주두포곡송납2.0 g(1차/d)、아기매소0.5 g (1차/d)화염산안추색30 mg(2차/d)。제4차정맥적주아기매소약30 min시,환자돌연출현흉민、별기。심전도시Ⅲ도방실전도조체。립즉정지약물수주,급여흡양。1h후,환자흉민、별기소실。5h 후복측심전도시두성심률。미재응용아기매소,환자미재출현유사증상。
An 86-year-old female patient with pulmonary infection was treated with IV infusions of ceftriaxone sodium 2. 0 g once daily,azithromycin 0. 5 g once daily,and ambroxol hydrochloride 30 mg twice daily. About 30 minutes after the fourth infusion of azithromycin,the patient abruptly developed chest tightness and suffocation. Electrocardiography showed Ⅲ degree atrioventricular block. Azithromycin was stopped immediately and she was treated with oxygen inhalation. One hour later,the symptoms of chest tightness and suffocation disappeared. Five hours later,a repeat electrocardiography showed sinus rhythm. Azithromycin was not given again and the similar symptoms did not recur any more.