药物不良反应杂志
藥物不良反應雜誌
약물불량반응잡지
ADVERSE DRUG REACTIONS JOURNAL
2014年
3期
175-176
,共2页
吕晓飞%年敏%李海芹%邱肃
呂曉飛%年敏%李海芹%邱肅
려효비%년민%리해근%구숙
左氧氟沙星%房室传导阻滞
左氧氟沙星%房室傳導阻滯
좌양불사성%방실전도조체
Levofloxacin%Atrioventricular block
1例21岁女性患者因急性胃肠炎静脉滴注左氧氟沙星0.4 g,1次/d。第3次静脉滴注过程中,患者突然出现心慌、胸闷、头晕。急查心电图,示心率39次/min,Ⅲ度房室传导阻滞,交界性逸搏及室性逸搏。立即停用左氧氟沙星,26 min后Ⅲ度房室传导阻滞转为Ⅰ度房室传导阻滞,心率58~66次/min。
1例21歲女性患者因急性胃腸炎靜脈滴註左氧氟沙星0.4 g,1次/d。第3次靜脈滴註過程中,患者突然齣現心慌、胸悶、頭暈。急查心電圖,示心率39次/min,Ⅲ度房室傳導阻滯,交界性逸搏及室性逸搏。立即停用左氧氟沙星,26 min後Ⅲ度房室傳導阻滯轉為Ⅰ度房室傳導阻滯,心率58~66次/min。
1례21세녀성환자인급성위장염정맥적주좌양불사성0.4 g,1차/d。제3차정맥적주과정중,환자돌연출현심황、흉민、두훈。급사심전도,시심솔39차/min,Ⅲ도방실전도조체,교계성일박급실성일박。립즉정용좌양불사성,26 min후Ⅲ도방실전도조체전위Ⅰ도방실전도조체,심솔58~66차/min。
A 21-year-old female with acute gastroenteritis received an intravenous infusion of levofloxacin 0. 4 g,once daily. She developed palpitation,sense of suppression in the chest and dizzy suddenly during the intravenous infusion on day 3. Electrocardiographic examination showed the following results:heart rate 39 times/min,third degree atrioventricular block,junctional escape beat and ventricular escape. Levofloxacin was withdrawn immediately. Twenty-six minutes later,third degree atrioventricular block converted to first-degree atrioventricular block and the heart rate was 58-66 times/min spontaneously.