中国医学前沿杂志（电子版）
中國醫學前沿雜誌（電子版）
중국의학전연잡지（전자판）
CHINESE JOURNAL OF THE FRONTIERS OF MEDICAL SCIENCE(ELECTRONIC VERSION)
2014年
6期
85-87
,共3页
妊娠%高血压%硝苯地平%硝酸甘油%硫酸镁
妊娠%高血壓%硝苯地平%硝痠甘油%硫痠鎂
임신%고혈압%초분지평%초산감유%류산미
Pregnancy%Hypertension%Nifedipine%Nitroglycerin%Magnesium sulphate
目的：探讨硝苯地平联合硫酸镁、硝酸甘油联合硫酸镁治疗妊娠期高血压疾病的临床效果。方法105例妊娠期高血压疾病患者根据入院时间被随机分为3组：A组（硫酸镁组），B组（硝苯地平联合硫酸镁组），C组（硝酸甘油联合硫酸镁组）。A组患者单纯使用硫酸镁静脉滴注降压，B组和C组患者在此基础上给予10 mg硝苯地平口服（每6小时1次）或用微量泵静脉注射硝酸甘油。分析3种不同用药方式的疗效。结果治疗后，3组患者血压均低于治疗前（P＜0.05），且B组和C组降压效果优于A组（P＜0.05）；B组和C组患者自然分娩比率显著高于A组（P＜0.05)；B组和C组患者不良反应发生率和妊娠结局与A组患者比较差异具有显著性（P＜0.05)；而B组和C组间各监测指标比较无显著差异（P＞0.05）。结论硝苯地平联合硫酸镁或硝酸甘油联合硫酸镁治疗妊娠期高血压疾病的临床效果均优于单独使用硫酸镁治疗，且二者均具有较好的安全性。
目的：探討硝苯地平聯閤硫痠鎂、硝痠甘油聯閤硫痠鎂治療妊娠期高血壓疾病的臨床效果。方法105例妊娠期高血壓疾病患者根據入院時間被隨機分為3組：A組（硫痠鎂組），B組（硝苯地平聯閤硫痠鎂組），C組（硝痠甘油聯閤硫痠鎂組）。A組患者單純使用硫痠鎂靜脈滴註降壓，B組和C組患者在此基礎上給予10 mg硝苯地平口服（每6小時1次）或用微量泵靜脈註射硝痠甘油。分析3種不同用藥方式的療效。結果治療後，3組患者血壓均低于治療前（P＜0.05），且B組和C組降壓效果優于A組（P＜0.05）；B組和C組患者自然分娩比率顯著高于A組（P＜0.05)；B組和C組患者不良反應髮生率和妊娠結跼與A組患者比較差異具有顯著性（P＜0.05)；而B組和C組間各鑑測指標比較無顯著差異（P＞0.05）。結論硝苯地平聯閤硫痠鎂或硝痠甘油聯閤硫痠鎂治療妊娠期高血壓疾病的臨床效果均優于單獨使用硫痠鎂治療，且二者均具有較好的安全性。
목적：탐토초분지평연합류산미、초산감유연합류산미치료임신기고혈압질병적림상효과。방법105례임신기고혈압질병환자근거입원시간피수궤분위3조：A조（류산미조），B조（초분지평연합류산미조），C조（초산감유연합류산미조）。A조환자단순사용류산미정맥적주강압，B조화C조환자재차기출상급여10 mg초분지평구복（매6소시1차）혹용미량빙정맥주사초산감유。분석3충불동용약방식적료효。결과치료후，3조환자혈압균저우치료전（P＜0.05），차B조화C조강압효과우우A조（P＜0.05）；B조화C조환자자연분면비솔현저고우A조（P＜0.05)；B조화C조환자불량반응발생솔화임신결국여A조환자비교차이구유현저성（P＜0.05)；이B조화C조간각감측지표비교무현저차이（P＞0.05）。결론초분지평연합류산미혹초산감유연합류산미치료임신기고혈압질병적림상효과균우우단독사용류산미치료，차이자균구유교호적안전성。
Objective To discuss the clinical effect of nifedipine combined with Magnesium sulfate, Magnesium sulfate plus nitroglycerin treatment of pregnancy-induced hypertension. Method According to the date of admission, 105 cases of patients with pregnancy-induced hypertension were randomly divided into 3 groups, group A:Magnesium sulfate group, group B:nifedipine combined with Magnesium sulfate group, group C:nitroglycerin combined with Magnesium sulfate group. Group A were treated with Magnesium sulfate intravenous infusion, based on this group B and group C patients were given 10 mg oral (every 6 hours 1) or a micro pump intravenous nitroglycerin. The curative effects of 3 groups were analyzed. Result Compared with before treatment, 3 groups of pregnant women blood pressure were all decrease (P<0.05), and group B and group C had lower blood pressure than group A (P<0.05);the natural birth rate in B group and C group were signiifcantly higher than that of group A (P<0.05);compared with group A, the adverse reaction rate and pregnancy outcome in group B and group C were statistically signiifcant (P < 0.05);the difference between group B and group C of monitoring index was not statistically signiifcant (P>0.05). Conclusion Nifedipine combined with Magnesium sulfate or nitroglycerin combined with Magnesium sulfate have more better clinical effects than that of Magnesium sulfate treatment of pregnancy induced hypertension, and both of the two have good safety.
