中国医学前沿杂志（电子版）
中國醫學前沿雜誌（電子版）
중국의학전연잡지（전자판）
CHINESE JOURNAL OF THE FRONTIERS OF MEDICAL SCIENCE(ELECTRONIC VERSION)
2014年
6期
53-56
,共4页
肿瘤复发%显微手术%鞍旁脑膜瘤%疗效
腫瘤複髮%顯微手術%鞍徬腦膜瘤%療效
종류복발%현미수술%안방뇌막류%료효
Tumor recurrence%Microsurgical operation%Parasellar meningioma%Curative effect
目的：研究显微手术治疗鞍旁脑膜瘤的临床效果及影响复发的因素。方法回顾性分析本院2008年11月至2012年11月治疗的268例鞍旁脑膜瘤患者的临床资料，全部患者均予显微手术治疗，对手术的切除程度、术后死亡率、并发症、患者生活质量及肿瘤复发等情况进行观察分析。结果不同范围切除术后，患者KPS对比呈显著性差异（P＜0.05）。WHO分级越高，其术后复发率越高；海绵窦侵犯患者术后复发较海绵窦未侵犯患者显著升高，差异具有显著性（P＜0.05），脑膜瘤间变型及非典型性患者术后的复发率较良性脑膜瘤患者显著升高，差异具有极其显著性（P＜0.01）。结论鞍旁脑膜瘤患者首选治疗为显微手术全切除，海绵窦受侵患者术后应予密切随访观察，脑膜瘤间变型及非典型性患者的复发风险较大，应于术后进行常规放射治疗。显微手术治疗鞍旁脑膜瘤远期疗效显著，应予推广。
目的：研究顯微手術治療鞍徬腦膜瘤的臨床效果及影響複髮的因素。方法迴顧性分析本院2008年11月至2012年11月治療的268例鞍徬腦膜瘤患者的臨床資料，全部患者均予顯微手術治療，對手術的切除程度、術後死亡率、併髮癥、患者生活質量及腫瘤複髮等情況進行觀察分析。結果不同範圍切除術後，患者KPS對比呈顯著性差異（P＜0.05）。WHO分級越高，其術後複髮率越高；海綿竇侵犯患者術後複髮較海綿竇未侵犯患者顯著升高，差異具有顯著性（P＜0.05），腦膜瘤間變型及非典型性患者術後的複髮率較良性腦膜瘤患者顯著升高，差異具有極其顯著性（P＜0.01）。結論鞍徬腦膜瘤患者首選治療為顯微手術全切除，海綿竇受侵患者術後應予密切隨訪觀察，腦膜瘤間變型及非典型性患者的複髮風險較大，應于術後進行常規放射治療。顯微手術治療鞍徬腦膜瘤遠期療效顯著，應予推廣。
목적：연구현미수술치료안방뇌막류적림상효과급영향복발적인소。방법회고성분석본원2008년11월지2012년11월치료적268례안방뇌막류환자적림상자료，전부환자균여현미수술치료，대수술적절제정도、술후사망솔、병발증、환자생활질량급종류복발등정황진행관찰분석。결과불동범위절제술후，환자KPS대비정현저성차이（P＜0.05）。WHO분급월고，기술후복발솔월고；해면두침범환자술후복발교해면두미침범환자현저승고，차이구유현저성（P＜0.05），뇌막류간변형급비전형성환자술후적복발솔교량성뇌막류환자현저승고，차이구유겁기현저성（P＜0.01）。결론안방뇌막류환자수선치료위현미수술전절제，해면두수침환자술후응여밀절수방관찰，뇌막류간변형급비전형성환자적복발풍험교대，응우술후진행상규방사치료。현미수술치료안방뇌막류원기료효현저，응여추엄。
Objective To study the microscopic operation treatment of sellar meningioma clinical effect and influence factors of recurrence. Method Retrospective analysis of our hospital from November 2008 to November 2012, 268 patients with parasagittal meningiomas treated in our department in patients with clinical data, all patients were treated with microsurgical operation treatment, observe and analyze the extent of resection, postoperative mortality of operation and clinical complications, quality of life of the patients with tumor recurrence, etc. Result After different range of resection, patients KPS contrast show signiifcant difference (P < 0.05). The higher the WHO classification, the postoperative recurrence rate was higher, Cavernous sinus violation less postoperative recurrence in patients with a significant rise in patients with cavernous sinus, with signiifcant difference (P<0.05), between the variant and atypical meningioma patients postoperative recurrence rate is signiifcantly increased in patients with benign meningiomas, has the extremely signiifcant difference (P<0.01). Conclusion The preferred treatment for patients with parasellar meningioma operation excision, cavernous sinus invasion in patients should be closely observed, greater risk of anaplastic and atypical meningioma recurrence, should be routine in postoperative radiotherapy. Micro operation treatment of parasellar meningioma long-term efifcacy, should be popularized.
