CAJ | 학술논문

文章从巧用大黄治疗腹泻的案例出发，分别从现代药理学研究及中医理论的角度阐释其作用机理，现代医学认为其止泻机理与所含鞣质成分及抗菌消炎作用有关，中医认为与气机升降及清热解毒功效相关。此外于大量温补涩肠药物之中，稍佐少量苦寒之大黄，可以防温肠止泻药物过于温涩。最后结合临床实践，从配伍环境、炮制方法、用量特点、煎服法、适应证、用药时间等方面，阐述了应用大黄止泻的体会。
문장종교용대황치료복사적안례출발，분별종현대약이학연구급중의이론적각도천석기작용궤리，현대의학인위기지사궤리여소함유질성분급항균소염작용유관，중의인위여기궤승강급청열해독공효상관。차외우대량온보삽장약물지중，초좌소량고한지대황，가이방온장지사약물과우온삽。최후결합림상실천，종배오배경、포제방법、용량특점、전복법、괄응증、용약시간등방면，천술료응용대황지사적체회。
The paper introduced the flexible application of Rhubarb in the treatment of diarrhea and the effect mechanism was explained in light of modern pharmacologic study and TCM theory. The modern medicine believes that the antidiarrheal mechanism is related to tannic acid contained in Rhubarb and its an-tibacterial and anti - inflammatory action. TCM holds that it is related to the action of herb itself,naming reg-ulating the ascending and descending of qi,clearing away heat and detoxification. Additionally,Rhubarb is bitter in flavor and cold in nature. The small dose of it may prevent from over warming and astringent action of the chief composition in the formula granules. The paper elaborated the experience in the application of Rhu-barb for the treatment of diarrhea in association with clinical practice,environment,processing,dose,decoc-ting method,indication and usage.