CAJ | 학술논문

提本文通过动物实验初步探讨了寒潮天气发生过程中对高血压疾病的影响。在张书余等（2013）研究的基础上，应用TEM1880气象环境模拟箱模拟寒潮温压变化，将27只健康大鼠按每组3个随机分为9组，分别为空白对照组、最低温前3 h组、最低温前1h组、最低温组、最低温后1h组、最低温后3h组、全过程结束组、全过程结束后5h组和全过程结束后7h组，放入模拟箱内，使其受寒潮天气影响，按照寒潮天气过程发生的不同时间先后分批取出实验大鼠，测量各组大鼠的收缩压、心率、体重，并通过腹主动脉采血测量血脂、去甲肾上腺素、血管紧张素Ⅱ及全血粘度等。实验结果分析表明，在寒潮天气发生过程中，冷锋通过后，受冷高压控制，气温迅速下降，当气温达到最低时，全血粘度、去甲肾上腺素和血管紧张素Ⅱ等上升到最大值，致使健康大鼠血压升高，并维持到寒潮天气影响结束以后还不能立刻恢复正常。
제본문통과동물실험초보탐토료한조천기발생과정중대고혈압질병적영향。재장서여등（2013）연구적기출상，응용TEM1880기상배경모의상모의한조온압변화，장27지건강대서안매조3개수궤분위9조，분별위공백대조조、최저온전3 h조、최저온전1h조、최저온조、최저온후1h조、최저온후3h조、전과정결속조、전과정결속후5h조화전과정결속후7h조，방입모의상내，사기수한조천기영향，안조한조천기과정발생적불동시간선후분비취출실험대서，측량각조대서적수축압、심솔、체중，병통과복주동맥채혈측량혈지、거갑신상선소、혈관긴장소Ⅱ급전혈점도등。실험결과분석표명，재한조천기발생과정중，랭봉통과후，수랭고압공제，기온신속하강，당기온체도최저시，전혈점도、거갑신상선소화혈관긴장소Ⅱ등상승도최대치，치사건강대서혈압승고，병유지도한조천기영향결속이후환불능립각회복정상。
Based on Zhang Shuyu’s research (2013),the impact of cold wave on hypertension disease is preliminarily discussed through the animal experiments.The cold wave process is simulated in the environ-mental test chamber (TEM1880).At the same time,27 healthy rats are randomly divided into the control group,3 hours beforeTmin(minimum temperature)group,1 hour beforeTmin group,Tmin group,1 hour af-terTmin group,3 hours afterTmin group,cold wave process group,5 hours after the cold wave process group,7 hours after the cold wave process group,respectively.Each group has 3 rats.All the groups ex-cept the control group are exposed to the cold environment and taken out in accordance with the developing progress of cold wave respectively.The following indexes are measured:systolic blood pressure (SBP), heart rate (HR),weight,blood lipid,noradrenaline (NA),angiotensin Ⅱ (Ang Ⅱ),whole blood viscos-ity (WBV),etc.The experimental results show that the air temperature decreases rapidly under the con-trol of the high pressure after cold front leaves in the cold wave process.WBV,NA and Ang Ⅱcan rise to the maximum value at theTmin ,making blood pressure increase in experimental rats in the whole time,and are hard to return to the original level even after the cold wave.