CAJ | 학술논문

目的：对胃肠间质瘤（GIST）临床病理特征与危险度分级的关系进行探讨。方法选取40例胃肠间质瘤患者作为研究对象，对患者的临床资料（如细胞形态、年龄性别、临床表现、发病部位、Ki-67、S-100、CD34、CD117以及α-SMA等）进行分析，并探讨GIST危险度分级与各项指标的相关性。结果调查发现，Ki-67指数、肿瘤坏死情况、肿瘤数目、周围组织有无粘连等指标与GIST危险度分级有着密切关系。结论研究得出，在胃肠间质瘤患者的危险度分级中，其危险程度主要取决于4个指标，分别是Ki-67指数、肿瘤坏死情况、肿瘤数目、周围组织有无粘连，因此在判断患者的预后情况、确定治疗方案时，应对这4各指标进行参考。
목적：대위장간질류（GIST）림상병리특정여위험도분급적관계진행탐토。방법선취40례위장간질류환자작위연구대상，대환자적림상자료（여세포형태、년령성별、림상표현、발병부위、Ki-67、S-100、CD34、CD117이급α-SMA등）진행분석，병탐토GIST위험도분급여각항지표적상관성。결과조사발현，Ki-67지수、종류배사정황、종류수목、주위조직유무점련등지표여GIST위험도분급유착밀절관계。결론연구득출，재위장간질류환자적위험도분급중，기위험정도주요취결우4개지표，분별시Ki-67지수、종류배사정황、종류수목、주위조직유무점련，인차재판단환자적예후정황、학정치료방안시，응대저4각지표진행삼고。
Objective of gastrointestinal stromal tumors (GIST)clinical and pathological features and risk classification relations were discussed. Methods stromal tumors among 40 cases of gastrointestinal patients as research subjects, the patient's clinical data(such as cellmorphology,age,sex,clinical manifestations,disease location,Ki-67,S-100,CD34,CD117,and α-SMA,etc.) analyze and explore GIST risk classification and relevance of the indicators. Results of the survey found, Ki-67 index,tumor necrosis, tumor number, and other indicators of the surrounding tissue adhesions and GIST risk classification has a close relationship. Conclusions of the study concluded that the risk of gastrointestinal stromal tumor grading patients, their degree of danger depends mainly on four indicators,namely,Ki-67 index,tumor necrosis,tumor number,without adhesions surrounding tissue,so determine the patient's prognosis,when determining the treatment plan,to deal with each of these four indicators reference.