CAJ | 학술논문

目的：探讨和分析舌癌的治疗方法及其预后的影响因素。方法对2001～2007年在中南大学口腔医学院和哈尔滨医科大学附属口腔医学院住院的1171例舌癌患者进行回顾性研究，对其年龄、性别、癌变部位、临床分期、病理分级、治疗方法等进行分析，探讨影响舌癌预后的因素。结果舌体癌患者生存率明显高于舌根癌；临床分期高、细胞分化程度低者其术后生存率较低；手术切缘阳性者、淋巴结转移者、骨受侵犯者其预后差；下颌骨的切除与否与预后无相关性（P＞0．05），术后即刻行皮瓣修复与否对生存率影响差异无统计学意义（P＞0．05）。结论切缘状况与临床分期是影响舌癌预后的独立因素，早期发现，早期诊断及治疗对提高舌癌患者的生存率有显著意义。
목적：탐토화분석설암적치료방법급기예후적영향인소。방법대2001～2007년재중남대학구강의학원화합이빈의과대학부속구강의학원주원적1171례설암환자진행회고성연구，대기년령、성별、암변부위、림상분기、병리분급、치료방법등진행분석，탐토영향설암예후적인소。결과설체암환자생존솔명현고우설근암；림상분기고、세포분화정도저자기술후생존솔교저；수술절연양성자、림파결전이자、골수침범자기예후차；하합골적절제여부여예후무상관성（P＞0．05），술후즉각행피판수복여부대생존솔영향차이무통계학의의（P＞0．05）。결론절연상황여림상분기시영향설암예후적독립인소，조기발현，조기진단급치료대제고설암환자적생존솔유현저의의。
Objective To investigate treatment and related prognostic factors of tongue carcinoma .Methods Clinical and patho-logical parameters of 1 171 cases of tongue carcinoma treated in Department of Oral and Maxillofacial Surgery ,School of Stomatolo-gy ,Harbin Medical University and Central South University from 2001 to 2007 were retrospective analyzed ,which included age , gender ,location ,pathological grade ,clinical TNM stages ,and treatment modality .Results After 3 to 5 year of follow-up ,survival rate of patients with tongue body carcinoma was obviously higher than that on the base of tongue .High clinical stage ,low cell dif-ferentiation degree of the postoperative patients had lower survival rate .The prognosis of patients with positive surgical margins and positive lymph node metastasis was poorer .The survival rate had no correlation with excision of mandible .When the tongue was re-stored with flaps ,the safety margins were increased to reduce recurrence .Conclusion Clinical TNM stages and surgical margin are independent prognostic factors for tongue cancer .Early diagnosis and treatment are vital to increase the survival rate of patients .