南通大学学报（医学版）
南通大學學報（醫學版）
남통대학학보（의학판）
JOURNAL OF NANTONG UNIVERSITY(MEDICAL SCIENCES)
2014年
5期
372-374
,共3页
感染性休克%预后%血乳酸%血小板%感染相关器官功能哀竭评分
感染性休剋%預後%血乳痠%血小闆%感染相關器官功能哀竭評分
감염성휴극%예후%혈유산%혈소판%감염상관기관공능애갈평분
septic shock%prognosis%lactate%platelet%sepsis-related organ failure assessment
目的：探讨与感染性休克死亡相关的常用临床指标。方法：将接受标准化治疗的118例感染性休克的成年患者按60 d内的存活情况分为死亡组和存活组，分别统计分析两组的临床指标，包括血压、心率、中心静脉压、慢性健康状况评分Ⅱ(acute physiology and chronic health evaluation scoring system，APACHEⅡ)、严重感染相关器官功能衰竭评分(sepsis-related organ failure assessment，SOFA)以及血乳酸、24 h血乳酸清除率等指标。结果：两组在年龄、收治时血乳酸水平、血小板水平、SOFA评分以及治疗后1 h的血压水平、24 h的血乳酸清除率等指标上差异具有统计学意义。结论：高龄、高乳酸血症、低血小板症、高SOFA分值、治疗后1 h仍存在的低血压值、低的24 h血乳酸清除率均与感染性休克患者的不良预后相关。。
目的：探討與感染性休剋死亡相關的常用臨床指標。方法：將接受標準化治療的118例感染性休剋的成年患者按60 d內的存活情況分為死亡組和存活組，分彆統計分析兩組的臨床指標，包括血壓、心率、中心靜脈壓、慢性健康狀況評分Ⅱ(acute physiology and chronic health evaluation scoring system，APACHEⅡ)、嚴重感染相關器官功能衰竭評分(sepsis-related organ failure assessment，SOFA)以及血乳痠、24 h血乳痠清除率等指標。結果：兩組在年齡、收治時血乳痠水平、血小闆水平、SOFA評分以及治療後1 h的血壓水平、24 h的血乳痠清除率等指標上差異具有統計學意義。結論：高齡、高乳痠血癥、低血小闆癥、高SOFA分值、治療後1 h仍存在的低血壓值、低的24 h血乳痠清除率均與感染性休剋患者的不良預後相關。。
목적：탐토여감염성휴극사망상관적상용림상지표。방법：장접수표준화치료적118례감염성휴극적성년환자안60 d내적존활정황분위사망조화존활조，분별통계분석량조적림상지표，포괄혈압、심솔、중심정맥압、만성건강상황평분Ⅱ(acute physiology and chronic health evaluation scoring system，APACHEⅡ)、엄중감염상관기관공능쇠갈평분(sepsis-related organ failure assessment，SOFA)이급혈유산、24 h혈유산청제솔등지표。결과：량조재년령、수치시혈유산수평、혈소판수평、SOFA평분이급치료후1 h적혈압수평、24 h적혈유산청제솔등지표상차이구유통계학의의。결론：고령、고유산혈증、저혈소판증、고SOFA분치、치료후1 h잉존재적저혈압치、저적24 h혈유산청제솔균여감염성휴극환자적불량예후상관。。
Objective: T o exp lore the common influencing factors associated with the outcome of septic shock. Methodes:118 septic shock patients who have a standardized treatment protocol of early goal directed therapy were divided into two groups(the death group and the survival group)by their survival situation in 60 days, recorded the clinical parameters of the patients, including blood pressure(BP), heart rate(HR), central venous pressure(CVP), acute physiology and chronic health evaluation scoring system(APACHE Ⅱ) score, SOFA(sepsis-related organ failure assessment) score, lactate and clearance rate of lactate in 24 h, all data were analyzed by statistical method. Results: There were remarkable statistical difference be-tween the death group and the survival group in age, basal lactate, basal platelet count, SOFA score, the BP level at one hour after treatment and the clearance rate of lactate in 24 h. Conclusion:Advanced age, hyperlactacidemia, thrombocytope-nia, high SOFA score, persistent low BP after the treatment of an hour and low clearance rate of lactate in 24 h were related to the poor prognosis of septic shock.
