CAJ | 학술논문

目的：探讨短暂性脑缺血发作（TIA）与颈动脉粥样硬化及其他影响因素间的关系。方法选择2010年6月～2013年6月我院神经内科收治的 TIA 患者60例为观察组，另选取同期健康体检者40例作为对照组，对两组间的相关生化指标检测及颈动脉彩色多普勒超声检查结果进行对比分析。结果观察组中吸烟、高血压、高血糖、肥胖、高脂血症、糖尿病的发生率均高于对照组，差异具有统计学意义（P<0.05）；观察组患者的 TC、LDL、FBG 及 Hcy 均高于对照组，HDL 含量低于对照组，差异具有统计学意义（P<0.05），两组 TG 含量相比无显著性差异（P>0.05）；观察组共41例检测出易损斑块，检出率为68.3％；对照组共7例检测出易损斑块，检出率为17.5％，两组比较差异具有统计学意义（P<0.05）。结论颈动脉粥样硬化斑块与 TIA 的发生密切相关，预防颈动脉粥样硬化斑块的发生能有效降低 TIA 的发病率，全面评估颈动脉粥样硬化斑块对于 TIA 的早期诊断和预后预测有非常重要的意义。
목적：탐토단잠성뇌결혈발작（TIA）여경동맥죽양경화급기타영향인소간적관계。방법선택2010년6월～2013년6월아원신경내과수치적 TIA 환자60례위관찰조，령선취동기건강체검자40례작위대조조，대량조간적상관생화지표검측급경동맥채색다보륵초성검사결과진행대비분석。결과관찰조중흡연、고혈압、고혈당、비반、고지혈증、당뇨병적발생솔균고우대조조，차이구유통계학의의（P<0.05）；관찰조환자적 TC、LDL、FBG 급 Hcy 균고우대조조，HDL 함량저우대조조，차이구유통계학의의（P<0.05），량조 TG 함량상비무현저성차이（P>0.05）；관찰조공41례검측출역손반괴，검출솔위68.3％；대조조공7례검측출역손반괴，검출솔위17.5％，량조비교차이구유통계학의의（P<0.05）。결론경동맥죽양경화반괴여 TIA 적발생밀절상관，예방경동맥죽양경화반괴적발생능유효강저 TIA 적발병솔，전면평고경동맥죽양경화반괴대우 TIA 적조기진단화예후예측유비상중요적의의。
Objective To investigate the relationship between transient ischemic attack and carotid atherosclerosis or other factors. Methods 60 cases of TIA patients treated in our hospital from Jun 2010 to Jun 2013 were selected as observa-tion group, concurrently with 40 health persons as control group. Compared the results of biochemical indexes detection and the carotid color Doppler ultrasonography between the two groups. Results The incidence of smoking, hypertension, hyper-glycemia, obesity, hyperlipidemia and diabetes mellitus in observation group were higher than those of control group, the differ-ences were statistically significant (P<0.05), the TC, LDL, FBG and Hcy of patients in observation group were higher than those of control group, the differences were statistically significant (P<0.05), HDL content of patients in observation group was lower than that of control group, the difference was significant (P<0.05), there was no significant difference in the content of TG between the two groups (P>0.05). Vulnerable plaque was detected in 41 cases and 7 cases with a detection rate of 68.3% and 17.5% in observation group and control group respectively, the difference was statistically significant (P<0.05). Conclusion Carotid atherosclerotic plaque is closely related to TIA. Preventing the occurrence of carotid atherosclerotic plaque can effectively reduce the incidence of TIA. Comprehensive evaluation on carotid atherosclerosis plaque is important for the early diagnosis and prognosis prediction of TIA.